Principal Scientist, Translational DMPK

1 week ago


Copenhagen, Copenhagen, Denmark H. Lundbeck AS Full time

Do you have experience as DMPK project representative within large molecule drug discovery projects? Then you might just be the new colleague that we are looking for. We have an opening for a Principal Scientist to join Translational DMPK. The department is part of the dynamic Research organization at Lundbeck located in Copenhagen.

Your new role – why is this a great opportunity?

As Principal Scientist you will be involved in guiding the DMPK optimization and characterization of new compounds in our discovery programs. In this role, you will closely interact with DMPK colleagues as well as discovery partners through participation in small multi-disciplinary drug discovery project teams. You will be involved in the entire DMPK discovery value chain from pharmacokinetic screening at early lead stage up to mechanistic and translational investigations at the stage of candidate selection with a focus on our large molecule discovery portfolio. Through your scientific oversight and collaborative spirit, you will play an important role in generating and interpreting value-adding DMPK data to advance our programs.

Your future team

In our department we interact closely with other Research functions such as antibody discovery and engineering, medicinal- and computational chemistry, pharmacology and toxicology to discover and optimize new molecules for CNS diseases. Our team is contributing and influencing the optimization of the DMPK properties of both small and large molecules from early target validation studies through Lead Optimization to selection, profiling, and risk assessment of clinical drug candidates. We are a mix of 14 skilled DMPK and bioanalysis scientists, lab technicians and students working closely together across projects. DMPK research studies and assays are conducted inhouse in modern DMPK and bioanalysis laboratories as well as at specialized CROs around the world. This is a great opportunity to join a research team committed to optimizing the DMPK properties and building the understanding of translation to humans for new molecules targeting CNS diseases.

The position is based at Lundbeck's headquarters in Valby, Copenhagen.

What you bring to the team

The position requires close scientific and operational coordination within the department as well as close collaboration with discovery project teams and other stakeholders in Research. You enjoy the combination of cross-functional project work, hands-on data analysis, and contributing to devising and implementing DMPK strategies. Further qualifications include:

  • PhD in relevant subject plus at least 6 years of experience in the field of small or large molecule DMPK in the pharmaceutical or biotech industry
  • Experience as DMPK project representative with ability to facilitate DMPK discovery strategies within large molecule-based research projects such as antibodies
  • Expertise with PK analysis of biologics is required as well as understanding of biologics PK/PD reasoning. Knowledge within analytical assays for measuring biologic molecules and biomarkers using mass spectrometry assays in preclinical study samples is desired.

Our promise to you

Lundbeck offers an inspiring workplace, passionate colleagues and a culture characterized as collaborative – a must to successfully bring our treatments through research and development all the way to commercialization and the people who need them. We offer a mix of exciting tasks and numerous development opportunities that are balanced with initiatives focused on your well-being.

Apply now

Can you see yourself in this role? We want to hear from you. Does this sound like your dream job, but you're not sure if you meet all the requirements? We still want to hear from you

Upload your CV and include a few lines about your motivation for applying. No separate cover letter is needed. We ask you not to include a photo or personal information that does not relate to your professional experience.

If you have questions or want to hear more, please feel free to contact Christoffer Bundgaard, Director, CHBG@lundbeck.com; +4530835785. Applications must be received by September 16.

We need every brain in the game – and that includes all brains and the different perspectives we bring to the table. At Lundbeck, we embrace the uniqueness of each employee, and we are committed to building a workforce that is as diverse as the people we serve.

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