Chemistry Innovation Lead

4 days ago


Copenhagen, Copenhagen, Denmark The Biopôle Full time
About the Position

We are seeking a senior medicinal chemist lead to join our team at The Biopôle. In this role, you will be responsible for leading our oral macrocycle discovery efforts, working closely with our biology, DMPK, and data science teams.

Key Responsibilities
  • Develop and execute strategies for designing orally available beyond-rule-of-5 macrocycles in collaboration with biology, DMPK, and data science colleagues.
  • Implement molecular design drivers supporting medchem optimization of drug properties for oral delivery of this new class of macrocycles.
  • Act as a medchem lead and/or discovery project lead, driving cross-functional collaborations and workflow establishment.
  • Engage closely with lab-active colleagues across disciplines and sites.
Requirements
  • PhD in chemistry, pharmaceutical sciences, or a related field.
  • 10+ years of industry experience in medicinal chemistry, including hit-to-lead, lead optimization, and drug candidate selection phases.
  • Extensive experience in medicinal chemistry and drug discovery, particularly in beyond-rule-of-5 therapeutics.
  • In-depth knowledge of the drug discovery process, particularly in the context of beyond-rule-of-5 therapeutics.
  • Strong collaboration, communication, and leadership skills in a cross-functional environment.


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