Postdoc of single molecule biophysics and single cell biophysics

Description of the scientific environment

The position is in the group of. Prof Nikos S Hatzakis. The group combines single protein biophysics, single cell biophysics and quantitative image analysis using machine learning to understand and control the role of protein dynamics on biomolecule recognition and cellular response regulation.

Short Project description

The post-doc will be working on establishing fluorescent microscopy assays often at the single molecule level to study the interaction of proteins with model membrane systems, and cellular membranes, as well as understanding at the cellular levels the mechanism underlying delivery of pharmaceutics. The post-doc will be using single particle fluorescence microscopy (TIRF and confocal as well as lattice light sheet microscopy), fluorescence lifetime imaging techniques, and quantitative image analysis. The post-doc will be interacting tightly with machine learning analysis of my group and collaborating groups, single cell biophysics. The post may also include performance of other duties.

Formal requirements

In order to be considered, the applicant must have:

• A PhD degree in either biophysics, chemistry, nanoscience, or a similar field.
• A documented experience in:
• Fluorescence microscopy and fluorescence lifetime imaging microscopy
• Assembling new microscopy setups
• Statistical analysis and computational image analysis.
• Writing and understanding scientific software including Matlab and Python for quantitative image analysis, and treating large datasets.
• Cell culturing, handling, and use for live cell fluorescence microscopy imaging.
• Molecular biology (PCR, traditional/Gibson assembly cloning, purification, and SDS/agarose electrophoresis).
• Biomolecule characterization preferably at the single molecule level
• Interaction of biologicals with membrane and delivery in cells
• Spectroscopy and FRET
• Excellent and documented English communication skills
• The ideal candidate should have a strong publication record, be able to work independently within an international cross-disciplinary group, and have to supervise students.

Skills of additional interest include

• Expertise in single molecule microscopy, fluorescence lifetime imaging, and analysis of microscopy datasets
• Expertise in molecular biology and protein characterization
• Previous experience in single molecule fluorescence microscopy building
• Experience with handling model membrane systems (liposomes)
• Documented expertise of working in an international multicultural environment
• Documented good teaching skills
• Experience with graphical programs for preparing compelling scientific figures

The postdoc's duties will include research within single cell biophysics as well as teaching. The post may also include performance of other duties.

Further information on the Department is linked at Inquiries about the position can be made to

The position is open from 01/02/2026or as soon as possible thereafter.

The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.

Terms of employment

The position is covered by the Memorandum on Job Structure for Academic Staff.

Terms of appointment and payment accord to the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State.

Negotiation for salary supplement is possible.

The application, in English, must be submitted electronically by clicking APPLY NOW below.

Please include

• Curriculum vitae
• Diplomas (Master and PhD degree or equivalent)
• Research plan – description of current and future research plans
• Complete publication list
• Separate reprints of 3 particularly relevant papers

The deadline for applications is 30. October 2025.

After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Interview Committee.

Interviews will be held in week 49.

You can read about the recruitment process at

Københavns Universitet giver sine knap medarbejdere muligheder for at udnytte deres talent fuldt ud i et ambitiøst, uformelt miljø. Vi sikrer traditionsrige og moderne rammer om uddannelser og fri forskning på højt internationalt niveau. Vi søger svar og løsninger på fælles problemer og gør ny viden tilgængelig og nyttig for andre.

Nikos Hatzakis

E-mail:

Ansøgningsfrist:

Ansættelsesdato:

Arbejdstid: Fuldtid

Afdeling/Sted: Department of Chemistry