Chemical/Process Engineer for CMC Chemical Development

Found in: Talent DK C2 - 2 weeks ago


Bagsværd, Denmark Novo Nordisk AS Full time

Are you motivated by joining an expanding area within chemical manufacturing, which is strategically important for shaping the future of Novo Nordisk? Are you passionate about designing and optimising synthetic routes for active pharmaceutical ingredients (API)? And do you have experience in mechanistic modelling and process design?

We are looking for a Chemical/Process Engineer to join our team in CMC Chemical Development – a part of CMC API Development. If you are ready to shape the future of bioprocessing and make a difference in the pharmaceutical industry, read on and apply today for a life-changing career.

Get introduced to CMC Chemical Development and meet some of our employees by visiting our career site

The position

As our new Chemical/Process Engineer, you will be instrumental in designing and optimizing synthetic routesfor the API. You will work closely with a diverse team of chemists, engineers and analytical scientists to ensure robust drug substance manufacture. Furthermore, your main responsibilities will include:

Developing mechanistic models for chemical steps such as reaction, filtration, distillation, extraction, and crystallization. Establishing a Digital Twins for the chemical modification steps. Exploring efficient algorithms for parameter fitting and implementing model-design of experiments. Supporting late-stage development activities, such as control strategy, fate & purge study, PAR, FMEA. Supporting technology transfer to manufacturing sites and process scale-up activities.

This position gives you a great opportunity to play a part in shaping the future of bioprocessing in close collaboration with a broad variety of stakeholder teams in development, production, and research.

Qualifications

You have a PhD in (chemical) engineering with experience in mechanistic modelling of complex systems based on experimental data supplemented with +3-5 years of experience in the life science industry, preferably in process development and scale-up. Furthermore, you should have:

Strong mathematical and analytical skills, with the ability to formulate mathematical models based on differential equations and apply them using simulation. Good understanding of unit operations such as mixing, crystallization, distillation, liquid-liquid extraction and drying. Experience with chemical process development scale-up and/or technical transfer. Knowledge of process safety and Good Manufacturing Practice (GMP) principles. Proficiency in modelling software such as Aspen Plus, DynoChem, gPROMS, SuperPro, PRO/II and programming skills in MatLab, Python, or Julia. Fluent in English, both written and spoken.

As a person, you posses exellent communication skills and the ability to present complex results in a clear and concise manner. With a solution-oriented mindset you have a strong practical capability to translate theory into real solutions. Your positive attitude enables you to work efficiently, whether as a team player or independently, even when dealing with complex tasks, to ensure timely progress.

You will become part of an international and dynamic team with highly talented and motivated colleagues. We have an informal working environment, a strong culture of cross-functional collaboration and knowledge sharing as well as focus on well-being and flexibility in workplace and hours.

About the area

As part of Novo Nordisk PSQIT organisation, Chemistry, Manufacturing and Control (CMC) Development & Scaling makes a real difference for patients with chronic diseases across the world. We develop, manufacture and distribute drug candidates for clinical trials and have a strong culture with a “can do” mind-set.

In Chemical Development, we are responsible for developing the synthetic processes required to produce the active pharmaceutical ingredients (APIs) for Novo Nordisk's new and innovative product portfolio. These processes encompass chemical modification of recombinantly-produced proteins, as well as chemical synthesis of peptides, oligonucleotides, small molecules and novel excipients. Our work spans various stages of development, from clinical trials to commercial manufacturing.

Our team in Chemical Development currently consists of 80+ chemists and laboratory technicians, and we have access to state-of-the-art chemistry laboratory facilities in Bagsværd (DK) and offices in Boston (USA). Our facilities enable us to support various types of work, including isotope chemistry, scale-up productions, and standard process development.


  • Chemical/Process Engineer for CMC Chemical Development

    Found in: Talent DK C2 - 2 weeks ago


    Bagsværd, Denmark Novo Nordisk Full time

    Are you motivated by joining an expanding area within chemical manufacturing, which is strategically important for shaping the future of Novo Nordisk? Are you passionate about designing and optimising synthetic routes for active pharmaceutical ingredients (API)? And do you have experience in mechanistic modeling and process design? We are looking for a...

  • Chemical/Process Engineer for CMC Chemical Development

    Found in: Talent DK C2 - 2 weeks ago


    Bagsværd, Denmark Novo Nordisk Full time

    The position As our new Chemical/Process Engineer, you will be instrumental in designing and optimizing synthetic routes for the API. You will work closely with a diverse team of chemists, engineers and analytical scientists to ensure robust drug substance manufacture. Furthermore, your main responsibilities will include: Developing mechanistic models...

  • Process Chemistry Scientists

    Found in: Talent DK C2 - 4 days ago


    Bagsværd, Denmark Novo Nordisk Full time

    The position We are looking for Process Chemistry Scientists at all levels (Job seniority depending on the experience of the candidate) who has a strong scientific and/or technical background in organic synthesis and/or GMP manufacturing of chemical entities at scale. The preferable candidate is experienced in process chemistry (with good knowledge of...

  • Technical CMC Writers

    Found in: Talent DK C2 - 3 days ago


    Bagsværd, Denmark Novo Nordisk Full time

    The position As a Regulatory Writer (seniority level depends on candidate experience), it will be your responsibility to define the regulatory storyline in collaboration with Regulatory Affairs. You will create documentation for our portfolio of products (TIDES and Small Molecules) to ensure that the required product quality is fulfilled and thereby...

  • Postdoc for Chromatography Process Research

    Found in: Talent DK C2 - 1 week ago


    Bagsværd, Denmark Novo Nordisk AS Full time

    Have you worked with modelling of adsorption processes and used Akta or similar FPLC platforms? Are you interested in peptide interaction and adsorption phenomena, and are you willing to take a deep dive into the underlying biophysics? Then you could be our new colleague in Downstream Development. We offer at two-year position as Postdoc within adsorptive...

  • Equipment responsible in API purification pilot facility

    Found in: Talent DK C2 - 4 days ago


    Bagsværd, Denmark Novo Nordisk Full time

    The position will contain a mixture of both practical and documentation tasks. You will be working closely together with the pilot production team, consisting of pilot scientists and process technicians, as well as stakeholders across the organisation (QA, IT & Automation, Calibration, etc.). You will be assigned the responsibility for specific pieces...

  • Investment/Capex Project Manager, CMC Development

    Found in: beBee jobs DK - 3 weeks ago


    Bagsværd, Denmark Novo Nordisk AS - Nn1 Full time

    Are you an experienced Project manager? Do you want to drive investment projects and handle a portfolio of smaller projects in close cooperation with Operation? If yes, then this might be the right role for you. Apply today The investment project portfolio in CMC Development and Scaling is growing and there is a need for more Project Managers to drive it....

  • Associate Manager, Cultivation Pilot Plants

    Found in: Talent DK C2 - 17 hours ago


    Bagsværd, Denmark Novo Nordisk AS Full time

    x Are you a strong people leader motivated by building the right team and making it thrive and perform? Do you have an urge to make complex processes simple and effective with a natural focus on optimizations/LEAN? If you are looking for a position in a high-paced and dynamic environment that combines both daily operations and long-term improvements,...

  • Investment/Capex Project Manager, CMC Development

    Found in: beBee S DK - 4 weeks ago


    Bagsværd, Denmark Novo Nordisk AS - Nn1 Full time

    Are you an experienced Project manager? Do you want to drive investment projects and handle a portfolio of smaller projects in close cooperation with Operation? If yes, then this might be the right role for you. Apply today!  The investment project portfolio in CMC Development and Scaling is growing and there is a need for more Project Managers to...

  • Associate Manager, Cultivation Pilot Plants

    Found in: Talent DK C2 - 17 hours ago


    Bagsværd, Denmark Novo Nordisk Full time

    The position We're expanding our Cultivation Pilot Plants to increase production output of Active Pharmaceutical Ingredients (API) for clinical and development trials. As an Associate Manager, you'll lead a team of 15 scientists and technicians responsible for preparing, executing, and assigning status to API production campaigns. As an Associate...

  • Equipment responsible in API purification pilot facility

    Found in: Talent DK C2 - 4 days ago


    Bagsværd, Denmark Novo Nordisk AS Full time

    Would you like to help us secure the operations of our pilot plants within a growing portfolio of pharmaceutical products? Do you want to expand your knowledge within pilot production and equipment used to purify APIs of the future? If yes, then you could be our new colleague as Equipment responsible. Apply today and join us for a life-changing career! ...

  • Cleaning Development Scientist

    Found in: beBee S DK - 4 weeks ago


    Bagsværd, Denmark Novo Nordisk AS - Nn1 Full time

    Do you want to initiate and drive exciting new initiatives to transform how we work with the cleaning of production equipment? Are you ready to establish new cleaning standards and simplify our processes to ensure the right quality at the right price for the stakeholders? Are you attentive to details, and enjoy working with numbers and formulas? Then...


  • Bagsværd, Denmark Novo Nordisk AS Full time

    JobbeskrivelsePlacering Bagsværd, DenmarkJobkategori Engineering & Technical Ansøg nu Are you looking for a life-changing career within Pharmaceutical Manufacturing? Novo Nordisk is a global healthcare company employing 50,000 employees worldwide. At our many different sites in the Greater Copenhagen area, we are hiring Maskinmester/Marine Engineers.Are...


  • Bagsværd, Denmark Novozymes Full time

    Welcome to Global Optimization, Research & Development, Bagsværd Global Optimization is looking for an ambitious Student Assistant who is passionate about biotechnology and data science. Global Optimization is a function in Product & Process Development, Research & Development and dedicated to optimizing our production processes at Novozymes. Our production...

  • Project Manager

    Found in: Talent DK C2 - 2 weeks ago


    Bagsværd, Denmark Novo Nordisk AS Full time

    Are you good at coordinating projects and managing stakeholders to ensure focus on strategic priorities and efficient execution? Do you want to play a central role in developing our future Container Closure Integrity (CCI) setup for diabetes and obesity products in Novo Nordisk?   Then you might be the right candidate for a job as Project Manager in our...

  • Cleaning Development Scientist

    Found in: beBee jobs DK - 2 weeks ago


    Bagsværd, Denmark Novo Nordisk AS - Nn1 Full time

    Do you want to initiate and drive exciting new initiatives to transform how we work with the cleaning of production equipment? Are you ready to establish new cleaning standards and simplify our processes to ensure the right quality at the right price for the stakeholders? Are you attentive to details, and enjoy working with numbers and formulas? Then join us...

  • Lead Automation Engineer for API Pilot Expansion

    Found in: beBee S DK - 4 weeks ago


    Bagsværd, Denmark Novo Nordisk AS - Nn1 Full time

    The position We are scaling up our API production capacity by expansions, upgrades, and increasing the automation level of our processes to be ready for Novo Nordisk’s current and future products to be used in clinical trials. As Lead Automation Engineer, you have an unparalleled opportunity to join us building several new API manufacturing...

  • Cleaning Development Scientist

    Found in: beBee S DK - 3 weeks ago


    Bagsværd, Denmark Novo Nordisk AS - Nn1 Full time

       Do you want to initiate and drive exciting new initiatives to transform how we work with the cleaning of production equipment? Are you ready to establish new cleaning standards and simplify our processes to ensure the right quality at the right price for the stakeholders? Are you attentive to details, and enjoy working with numbers and formulas? Then...

  • Process Engineer for Aseptic Production

    Found in: beBee jobs DK - 2 weeks ago


    Bagsværd, Denmark Novo Nordisk AS Full time

    JobbeskrivelsePlacering Lyngby, DenmarkJobkategori Manufacturing Ansøg nu Do you have expertise within aseptic production and are looking to offer your experience within the development of the future Aseptic Processing facilities? Are you looking for a global position where you can drive material handling processes and equipment standards globally? Are you...

  • Postdoc for Chromatography Process Research

    Found in: Talent DK C2 - 1 week ago


    Bagsværd, Denmark Novo Nordisk Full time

    The job is placed in CMC API Development located in Bagsværd, Denmark. Our main responsibility is to develop manufacturing processes for new proteins and peptides in close collaboration with the research and manufacturing units. You will be part of a small research group in Downstream Development focusing on expanding our knowledge and developing our...