Researcher position in the Hickson Group at the DNRF Center for Chromosome Stability

2 weeks ago

Copenhagen, Copenhagen, Denmark Københavns Universitet (KU) Full time

A position as a Researcher is available in the Center for Chromosome Stability (CCS) (www.ccs.ku.dk) in the group headed by Prof. Ian Hickson. The post is available from 1st January 2025 or after agreement. Highly motivated and committed candidates with an interest in chromosome mechanics and biology are encouraged to apply.

The Center for Chromosome Stability
The CCS is a Center of Excellence funded by the Danish National Research Foundation (DNRF) and its mission is to advance our understanding of how chromosomal instability causes human disease. The CCS is embedded at the Department of Cellular and Molecular Medicine (https://icmm.ku.dk/english/). The working language in the CCS is English.

Our group and research
The Hickson group (https://icmm.ku.dk/english/research-groups/hickson-group/) aims to understand the molecular mechanisms that cells use to maintain genome stability, using a combination of genetic, biochemical and cell biology approaches. The research in the Hickson group is generously supported by the Danish National Research Foundation.

Project description
The successful candidate will analyse the mechanical properties of native human chromosomes using optical tweezers and analyse the effect in human cells of manipulating enzymes that alter the mechanical properties of chromosomes.

Start date: 1 January 2025
Duration: 8 months
Weekly working hours: 37

Key criteria for the assessment of applicants

  • Applicants should hold a PhD degree in biochemistry, cell biology, biophysics, protein chemistry or a related discipline, preferably with a background in DNA replication or repair, mitosis, cell cycle or another area of chromosome biology. Extensive postdoctoral experience is also required.
  • Significant expertise in two or more of the following techniques: optical manipulation of chromosomes, advanced imaging or protein degron analysis in human cells.
  • Several primary papers published in reputable scientific journals, ideally as first author.
  • A high degree of motivation, enthusiasm and attention to detail.
  • Excellent communication skills, including the ability to write for publication, present research proposals and results, and fluency in written and spoken English.

Place of employment
The place of employment is the Center for Chromosome Stability (CCS), Department of Cellular and Molecular Medicine (ICMM), Panum Institute, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and access to state-of-the-art equipment.

Terms of employment
The average weekly working hours are 37 hours per week. The position is a fixed-term position limited to a period of 8 months. The start date is 1 January 2025 or after agreement.

Questions
For specific information about the position, please contact Ian Hickson by e-mail: iandh@sund.ku.dk. For further general questions about the position, please contact Elin Oelgaard by e-mail: ee@sund.ku.dk.

Application procedure
Your application must be submitted in English by clicking 'Apply now' below. Furthermore, your application must include the following documents/attachments – all in PDF format:

  • Motivated letter of application (max. one page)
  • CV incl. education, work/research experience, language skills and other skills relevant for the position
  • A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do
  • List of publications
  • Teaching portfolio (If applicable)

Deadline for applications: Wednesday 18 September 2024, 23.59 p.m. CET
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

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