Postdoc in Genetic Regulation of the Plasma Proteome and its Link to Cardiometabolic Disease in
2 days ago
The University uses third-party technologies to register user behaviour on the website (statistics) to keep improving our service. The University also uses third-party technologies to promote degree programmes, courses, conferences and exhibitions on websites and social media to show you the most relevant offers.
Postdoc in Genetic Regulation of the Plasma Proteome and its Link to Cardiometabolic Disease in Greenlandic InuitNovo Nordisk Foundation Center for Basic Metabolic Research
Faculty of Health and Medical Sciences
University of Copenhagen
The University of Copenhagen is seeking a highly motivated and talented Postdoc fellow to commence on February 1, 2025, or after agreement in the Hansen Group at the Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR), University of Copenhagen.
About Us
The Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR) is an academic research Center that pioneers groundbreaking research towards better cardiometabolic health. Through collaborative interdisciplinary research from single-cell genomics to whole-body systems, CBMR aims to transform the basic understanding of cardiometabolic health and accelerate its translation into prevention and treatment strategies. The Center's uniquely multi- and interdisciplinary approach combines research in genetics, physiology and pharmacology, to better understand the complex interplay of the many factors that drive cardiometabolic disease.
Our Research
In the molecular understanding of metabolic diseases, a major gap exists between basic genetic and microbiome discoveries and their impact on physiology and the potential for clinical translation. The Hansen Group aims to bridge this gap by connecting genomic discoveries and epidemiology, with physiology and clinical application. To study the role of selected genetic variants in human metabolism, we perform physiology and intervention studies based on recruit-by-genotype principles.
Job Description
Genome-wide association studies (GWAS) have laid the framework for understanding the impact of genetic variation on complex disease risk, predominantly identifying common variants with small effects. Studying isolated populations has the power to enhance the discovery of disease-associated loci, due to the enrichment of certain rare variants with large effects. Circulating proteins provide deep insights into the current state of human health and can capture the influence of environment on disease pathogenesis. The Postdoc will work on a project that will integrate high-throughput mass spectrometry (MS)-based plasma proteomics data with electronic health registry data, along with genetic information from 4,180 Greenlandic individuals to drive the discovery of novel clinical biomarkers and therapeutic targets which may aid in the future prevention and treatment of cardiometabolic diseases, including obesity, type 2 diabetes (T2D), and cardiovascular diseases (CVDs).
Your tasks will be to:
- Examine baseline and longitudinal associations between the MS-based plasma proteome and cardiometabolic disease outcomes using registry-based data.
- Perform a GWAS of the MS-based plasma proteome to identify protein quantitative trait loci (pQTLs).
- Examine the overlap between pQTLs and cardiometabolic disease-associated risk variants using colocalization methods.
- Coordinate project-related tasks.
- Contribute to scientific papers.
Profile
The Postdoc fellowship is aimed at early-career researchers with a background in data science or bioinformatics and familiar with integrative research approaches within the broad area of basic cardiometabolic research.
Required qualifications:
- PhD in bioinformatics, computational biology, statistical genomics or similar.
- Proficiency in a high-level programming language such as R or Python.
- Experience in applying statistical methods to proteomic and/or genomic data.
- Experience from working with large genomic datasets.
- Proven track record showing scientific productivity in peer-reviewed journals.
- Excellent English communication skills, both written and oral.
Eligibility
The Postdoc fellowships within the CBMR International PhD & Postdoc Program are open for applicants that hold a PhD degree awarded from a university outside of Denmark. The program is also open for applicants with a Danish PhD degree who can document at least 12 months of full-time research experience from outside Denmark during or after the PhD studies. The PhD degree has to be obtained before February 1, 2025.
Terms of Employment
The employment as Postdoc is a full-time position for 3 years. Starting date is February 1, 2025, or after agreement.
Application Procedure
Your online application must be submitted in English via the 'Apply now' link below. Furthermore, your application must include the following documents/attachments – all in PDF format:
- Cover letter expressing the motivation and previous research experience of the applicant (max. one page)
- Copy of the PhD degree certificate and the master's degree certificate. In case the PhD has not yet been completed, a written statement from the supervisor is acceptable, confirming it will be obtained before February 1, 2025.
- List of publications
- References (name and contact details of at least two references)
Application Deadline: September 20, 2024, 23.59pm CET.
The University of Copenhagen wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of their personal backgrounds.
#J-18808-Ljbffr-
Copenhagen, Copenhagen, Denmark Københavns Universitet Full timeThe University of Copenhagen is seeking a highly motivated and talented Postdoc fellow to work on a project that will integrate high-throughput mass spectrometry (MS)-based plasma proteomics data with electronic health registry data, along with genetic information from 4,180 Greenlandic individuals.About UsThe Novo Nordisk Foundation Center for Basic...
-
Data Scientist in Cardiometabolic Research
2 days ago
Copenhagen, Copenhagen, Denmark Københavns Universitet Full timeThe University of Copenhagen is a leading academic research institution that pioneers groundbreaking research towards better cardiometabolic health. Our research aims to transform the basic understanding of cardiometabolic health and accelerate its translation into prevention and treatment strategies.Job DescriptionWe are seeking a highly motivated and...
-
Bioinformatics Expert in Genomic Studies
2 days ago
Copenhagen, Copenhagen, Denmark Københavns Universitet Full timeWe are seeking a highly motivated and talented Postdoc fellow to work on a project that will integrate high-throughput mass spectrometry (MS)-based plasma proteomics data with electronic health registry data, along with genetic information from 4,180 Greenlandic individuals.About UsThe Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR) is an...
-
Postdoc Researcher in Cardiometabolic Health
5 days ago
Copenhagen, Copenhagen, Denmark Københavns Universitet Full timeCompany OverviewKøbenhavns Universitet is a leading academic research center that pioneers groundbreaking research towards better cardiometabolic health. Our mission is to transform the basic understanding of cardiometabolic disease and accelerate its translation into prevention and treatment strategies.We are committed to fostering a collaborative and...
-
Copenhagen, Copenhagen, Denmark Københavns Universitet (KU) Full timeAbout UsThe Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR) is a pioneering academic research center that aims to transform the basic understanding of cardiometabolic health and accelerate its translation into prevention and treatment strategies.We combine research in genetics, physiology, and pharmacology to better understand the complex...
-
Copenhagen, Copenhagen, Denmark Københavns Universitet (KU) Full timeResearch OpportunitiesThe Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR) offers a unique opportunity to conduct cutting-edge research in cardiometabolic disease modeling using multi-omics and multi-modal data. Our research team uses advanced computational algorithms and machine learning techniques to analyze and integrate large datasets...
-
Proteomics Research Scientist
5 days ago
Copenhagen, Copenhagen, Denmark Københavns Universitet Full timeThe Cardiac Proteomics Group at the Department of Biomedical Sciences is seeking a talented postdoctoral fellow to investigate protein regulations involved in cardiometabolic syndrome.Job DescriptionThe research fellow will explore remodeling in hearts from animal models, patient samples, and cell systems using quantitative proteomics-based approaches to...
-
Postdoc in Adipose tissue crosstalk
5 days ago
Copenhagen, Copenhagen, Denmark Københavns Universitet Full timeFaculty of Health and Medical Sciences University of Copenhagen The University of Copenhagen is seeking a highly motivated and talented Postdoc fellow to commence on February 1, 2025, or after agreement in the Schéele Group at the Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR), University of Copenhagen. About Us The Novo Nordisk...
-
Copenhagen, Copenhagen, Denmark Københavns Universitet Full timePostdoctoral Fellow for Mass Spectrometry Based Proteomics Investigation of Disease Mechanisms Job Description The Cardiac Proteomics Group at the Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen seeks to appoint a talented postdoctoral fellow to outline protein regulations involved in the pathogenesis of...
-
Proteomics Researcher for Disease Mechanisms
2 days ago
Copenhagen, Copenhagen, Denmark Københavns Universitet Full timeAbout the PositionWe are looking for a talented postdoctoral fellow to contribute to our research on cardiac pathophysiology. The successful candidate will work on identifying molecular changes driving the disease state using quantitative proteomics-based approaches. This involves investigating remodeling in hearts from animal models, patient samples as well...
-
Postdoc in adipose mitochondrial biology
5 days ago
Copenhagen, Copenhagen, Denmark Københavns Universitet Full timeNovo Nordisk Foundation Center for Basic Metabolic ResearchUniversity of Copenhagen The University of Copenhagen is seeking an experienced Postdoc fellow to commence on December 1, 2024, or after agreement, for the Gerhart-Hines Group at the Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR), University of Copenhagen. About Us The Novo...
-
Copenhagen, Copenhagen, Denmark Københavns Universitet Full timeThe University uses third-party technologies to register user behaviour on the website (statistics) to keep improving our service. The University also uses third-party technologies to promote degree programmes, courses, conferences and exhibitions on websites and social media to show you the most relevant offers. Postdoc Positions in Proteomics and Genomics...
-
Copenhagen, Copenhagen, Denmark Københavns Universitet Full timeComputational and Experimental Researcher in Human Intestinal Gut Microbiome and Plasma Metabolome Research Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen We are seeking a highly motivated and dynamic Researcher with competence in both computational analysis and experimental rodent, cellular, and molecular experimental...
-
Copenhagen, Copenhagen, Denmark Københavns Universitet Full timeThe University uses third-party technologies to register user behaviour on the website (statistics) to keep improving our service. The University also uses third-party technologies to promote degree programmes, courses, conferences and exhibitions on websites and social media to show you the most relevant offers. Postdoctoral Fellowship in Bioinformatics,...
-
Copenhagen, Copenhagen, Denmark Københavns Universitet (KU) Full timeNovo Nordisk Foundation Center for Basic Metabolic Research ,University of Copenhagen We are looking to hire a highly motivated and dynamic Postdoc with a Ph.D. to join the Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Denmark. Candidates should have a strong background in bioinformatics, genomics, multi-omics...
-
Copenhagen, Copenhagen, Denmark Københavns Universitet (KU) Full timeAbout UsThe Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR) is an academic research center that pioneers groundbreaking research towards better cardiometabolic health. Through collaborative interdisciplinary research from single-cell genomics to whole-body systems, CBMR aims to improve our understanding of cardiometabolic health.We develop...
-
Copenhagen, Copenhagen, Denmark Københavns Universitet (KU) Full timeTwo highly attractive postdoctoral positions are available in the Choudhary group at the University of Copenhagen. About the groups The Choudhary lab is technically and internationally diverse and embedded in an excellent environment that supports high-quality research and encourages interdisciplinary collaboration. The Choudhary lab conducts research using...
-
Copenhagen, Copenhagen, Denmark Københavns Universitet Full timeJob DescriptionWe are seeking a highly motivated and dynamic Researcher with competence in both computational analysis and experimental rodent, cellular, and molecular experimental validation of human intestinal microbiome and plasma metabolome research.The position is anchored in the research team of Associate Professor Tune Pers at Novo Nordisk Foundation...
-
Copenhagen, Copenhagen, Denmark Københavns Universitet Full timeJob DescriptionWe are seeking a highly motivated postdoctoral fellow to join our team at the Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen. The successful candidate will be part of the Cardiac Proteomics group led by Professor Lundby and will work on investigating remodeling in hearts from animal models,...
-
Copenhagen, Copenhagen, Denmark Københavns Universitet (KU) Full timeNovo Nordisk Foundation Center for Basic Metabolic Research University of Copenhagen We are looking to hire a highly motivated and dynamic postdoc with a PhD to join the Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Denmark. Candidates should have a strong background in data science, epidemiology, bioinformatics,...