12 months Temporary Scientist
1 week ago
Our purpose is to bring hope to life by enabling life-changing therapies for patients around the globe, creating a healthier and happier tomorrow. Our mission is to work side by side with our customers in order to improve patients’ lives by bringing new biopharmaceuticals to market.
AGC is looking for a Scientist / Sen. Scientist with expertise and experience in characterization of protein-based biotherapeutics.
We are seeking a Scientist with an interest in analytical characterization of biotherapeutics, by employing methods such as peptide mapping by LC-MS/MS, intact mass analysis by mass spectrometry, N-linked glycan analysis by HILIC-FLD and quantification of detergents by LC-CAD detection.
The position will be anchored in the Characterization Team in the Analytical Development (AD) Department at the Copenhagen site of AGC Biologics A/S (AGC). AGC is a Contract Development and Manufacturing Organization with facilities in Denmark, Germany, Italy, Japan and USA and with customers all over the world.
The DepartmentThe AD Department consists of 42 dedicated and highly competent scientists and technicians working in four sub teams; characterization, chromatographic assay development, bioassay development and PD support. AD is responsible for:
- Implementation, transfer and development of analytical procedures
- Transfer of analytical methods to QC for validation
- Analytical support to upstream and downstream process development departments
- Characterization of biotherapeutic products and drug intermediates
- Testing engineering batches for production
AGC projects range from early pre-clinical development through all phases of clinical development to commercial supply. AD is also involved in cross-functional project groups and implementation of new analytical technologies and techniques. The AD department is in close contact with our counterparts in our Seattle (USA), Boulder (USA), Heidelberg (GER) and Chiba (JPN) facilities.
As a Scientist in the Characterization team, you will be working with developing analytical methods in several different characterization assays like intact mass analysis, peptide mapping and glycan analysis as well as various other chromatographic techniques. All in the quest to support a wide variety of protein-based drug products to support our customers getting a high-quality product to market as fast as possible. You will be working together with a team of 2 scientists and 4 technicians, and we can promise an exciting and diverse job.
The work environment in our department is very informal. There is constant collaboration across the organization, and all employees have a professional and flexible attitude towards their work.
Responsibilities And TasksYou will get the opportunity to work with a broad range of personalities as well as a diverse set of drug products in different clinical stages; you will also get the opportunity to use your skills in a cross-functional setting and interactive environment.
The Job Includes- Evaluating methods received from clients before method implementation at AGC.
- Developing analytical characterization methods for challenging biopharmaceuticals, including documentation of the methods.
- Performing "pre"-validations ensuring methods are suitable for use in QC.
- Processing and reviewing analytical results to support upstream and downstream process development.
- Troubleshooting of analytical methods and instruments.
The ideal candidate holds a degree in science, engineering, or a related field (MSc. Or PhD). You have practical experience with executing methods within LC-MS and/or chromatographic methodologies of proteins. In addition to this you have:
- Preferably +2 years of experience in analytics, from the biotech industry.
- Experience with and understanding of analytical instrumentation, e.g. HPLC and LC-MS systems.
- Experience with handling and analyzing biopharmaceuticals.
- Understanding of biopharmaceutical manufacturing and regulatory requirements.
- Ability to work independently in a dynamic environment.
- Good interpersonal and communication skills.
- Good English communication skills both oral and written.
Our culture at AGC Biologics is defined by the six core values: Knowledge, Trust, Quality, Ingenuity, Accountability and Teamwork. Our core values stem from our team members and are embedded into our DNA. They provide a common language and understanding of how we as an organization are connected across three continents. Our core values serve as a compass and reminder of how we achieve our purpose of bringing hope to life for patients around the globe.
AGC Biologics offers a highly competitive compensation package and a friendly, collaborative culture that values personal initiative and professional achievement. AGC Biologics is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to age, ancestry, color, family or medical care leave, gender identity or expression, genetic information, marital status, medical condition, national origin, physical or mental disability, political affiliation, protected veteran status, race, religion, sexual orientation, or any other characteristic protected by applicable laws, regulations and ordinances.
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