Senior/Principal Laboratory Technician

5 days ago

Hørsholm, Denmark Gubra ApS Full time
Senior/Principal Laboratory Technician (Laborant) for Drug Discovery Preformulation

Are you experienced in preformulation and stability assays? Are you eager to apply your experimental skills and expertise in drug discovery research? If so, we have an exciting opportunity for you at Gubra.

Gubra is seeking a Laboratory Technician (Laborant) to join our Preformulation Team within the Drug Profiling department. In this role, you will support both our internal and partnered drug discovery activities.

The Team

The Preformulation Team studies the physicochemical properties of novel peptide drug candidates, including solubility and physical/chemical stability, during the hit-to-lead and early development phases. We also support the Clinical Development department with early formulation and analytical expertise while contributing to Gubra’s automated drug screening platform, streaMLine. The department also provides bioanalysis expertise to advance Gubra’s drug discovery projects. Committed to innovation, we continuously develop preformulation assays to ensure the generation of high-quality data. The team consists of three scientists and one laboratory technician, collaborating closely within the department and across Gubra.

A Versatile Role with a Focus on Hands-On Laboratory Work

As a Laboratory Technician in our Preformulation Team, you will contribute to all stages of Gubra’s drug discovery programs by developing high-throughput assays and screening peptide drug candidates. You will collaborate closely with scientists and fellow laboratory technicians managing multiple projects simultaneously.

Your primary tasks will include:

  • Performing solubility, chemical, and physical stability studies in early and late drug discovery projects using reverse-phase and size-exclusion UPLC, dynamic light scattering (DLS), fluorescence (including Thioflavin T assays), and UV-VIS plate readers.
  • Conducting high-throughput physicochemical characterization of larger peptide drug libraries, including solubility, physical stability, and chemical stability studies for early drug discovery programs.
  • Processing data and documenting experiments.
  • Maintaining and organizing laboratory inventory in collaboration with fellow laboratory technicians to ensure smooth workflows.

Laboratory Technician with a Motivation for Teamwork

You thrive in a collaborative environment where teamwork and knowledge sharing are key to great results and enjoyable workdays. With an open mindset, you are adaptable to change and willing to contribute to workflows across departments. You maintain an organized and structured approach to your work, with a strong dedication to delivering high-quality data.

In addition, you can check the following boxes:

  • You hold a certified Laboratory Technician diploma or similar, preferably with 5+ years of experience.
  • Experience with one or more techniques such as UPLC (RP and SEC), UV-FL microplate readers, and DLS in a drug discovery or drug development setting.
  • Observant and proactive in the lab.
  • Motivated to work with automation, including pipetting robots/liquid handlers.
  • Proficient in data handling and reporting.
  • Good communication skills in both Danish and English.

We Offer:

  • A 37-hour workweek, including paid lunch breaks.
  • Flexible working hours – any overtime is exchanged for time off.
  • Many social initiatives, such as Friday breakfasts & morning workouts.

Contact and Application

Please apply via our website using the “Apply” button and uploading your motivated cover letter, resume (in Danish or English), and relevant diplomas. The deadline for application is January 23, 2025.

Candidates will be invited for interviews on a rolling basis, and we reserve the right to close the posting prior to the expiration date.

If you have any questions, you are very welcome to contact Department Manager, Jakob Plum Christensen at

We look forward to receiving your application.

#J-18808-Ljbffr

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