Scientific Researcher for Drug Interaction Studies

5 days ago


Copenhagen, Copenhagen, Denmark Lundbeck AS, H Full time

Lundbeck A/S, H is a leading pharmaceutical company that focuses on developing innovative treatments for brain disorders. As a Principal Scientist, you will be part of the Department of Drug Metabolism within the Non-Clinical Safety Research division.

Your main responsibilities will include evaluating the drug-drug interaction risk of Lundbeck development compounds, which involves close collaboration with colleagues in Clinical Pharmacology. You will also be responsible for planning, conducting, and reporting in vitro DDI studies as well as PBPK modeling and simulation.

In this role, you will manage various studies such as enzyme reaction phenotyping, enzyme inhibition, enzyme induction, transporter inhibition, transporter substrate evaluations, and mechanistic studies. You will work closely with Contract Research Organizations (CROs) who perform studies on behalf of Lundbeck, as well as our laboratories where you will be responsible for studies and spar with technicians.

You will represent the DDI group in project teams to ensure progress of our pipeline and drive science within the group together with your colleagues. Our team is based in Copenhagen, Denmark, and we pride ourselves on fostering scientific excellence, a collaborative work environment, open communication, continuous learning, and celebrating successes.

We are looking for a candidate with a PhD in biochemistry, pharmacy, chemical engineering or equivalent, and experience in enzymology, inhibition kinetics, and in vitro DDI studies. You should have hands-on experience with in vitro DDI assays and LC-MS, and experience with PBPK modeling and simulations would be an advantage. You should also have experience with DDI guidelines and regulatory summary documents preparation.



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