Uncover the Secrets of Cancer Cell Interactions

2 months ago

Herlev, Herlev Kommune, Denmark Nordic Bioscience Full time

About the Project

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This master thesis project focuses on developing a co-culture model of cancer-associated fibroblasts (CAFs) with cancer cells to investigate matrix remodeling within the tumor microenvironment (TME).

The primary objective is to examine how the interaction between CAFs and cancer cell lines influences the production and cleavage of collagen matrices.

Key Activities:

  • Literature Research: Conduct a comprehensive review of existing studies on CAFs, cancer cells, and ECM remodeling to establish a foundation for the experimental design.
  • Expansion and Characterization of Cancer Cells: Expand cancer cell lines and adapt them to the so-called

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