Senior Laborant for Purification Research

Found in: Talent DK C2 - 2 weeks ago


Måløv, Denmark Novo Nordisk Full time

Jobbet

Som laborant i Purification Research 2 vil dit primære ansvar være: Sikre levering af oprensede rekombinante peptider og proteiner til forskningsprojekter, der har til formål at identificere nye kliniske lægemiddelkandidater. Samarbejde med afdelingens forskere og laboranter om at etablere effektive oprensningsmetoder i laboratorieskala. Levering af oprensede peptider og proteiner ved hjælp af avancerede kromatografisystemer, membranteknologi og analytisk udstyr. Et afgørende aspekt af rollen vil være at rapportere og dokumentere dit arbejde og dine resultater i vores elektroniske laboratoriebogssystemer, samt at føre tilsyn med drift og vedligeholdelse af bestemt udstyr i afdelingen. Afhængigt af dit erfaringsniveau forventes det, at du arbejder selvstændigt og praktisk i laboratoriet, samtidig med at du lærer fra andre medlemmer af afdelingen. Niveauet for stillingen vil blive bestemt af dine kompetencer og tidligere erfaring. Kvalifikationer Du skal have en uddannelse som laborant eller tilsvarende samt flere års erfaring med proteinoprensning inden for farmaceutisk forskning. For at få succes i denne rolle forestiller vi os, at du har følgende: Erfaring med præparativ kolonnekromatografi. Praktisk erfaring med ÄKTA-oprensningssystemer og Unicorn-kontrolsoftware. Erfaring med grundlæggende analysemetoder, herunder SE-UPLC/RP-UPLC/LC-MS og dataanalyse. Tidligere erfaring med forskellige molekylære formater betragtes som en fordel. Evne til at tackle digitale udfordringer, systemer og software med en tankegang, der er orienteret mod løbende forbedringer. Det er nødvendigt, at du behersker engelsk, da sproget bruges i en stor del af kommunikationen i afdelingen. På det personlige plan skal du være en inkluderende holdspiller med evnen til at kommunikere klart og præcist med kolleger og interessenter. Du bør også have en nysgerrig og selvkørende personlighed, der opretholder en positiv holdning til udfordringer og trives i et uformelt og meget dynamisk arbejdsmiljø. Om Afdelingen Purification Research 2 er en af to oprensningsafdelinger i Bioprocess Research og fokuserer på oprensning af proteiner og peptider til de tidlige forskningsprojekter. Vi oprenser molekyler fra rekombinante ekspressioner, hvilket hjælper med udvikling og udvælgelse af kliniske kandidater. Vores ansvarsområder omfatter oprensning af udfordrende hjælpeproteiner, udførelse af automatiserede oprensninger og opresning af varianter fra milligram til gram skala. Vi understøtter også udvikling af cellelinjer og etablerer indledende oprensningsprocesser til overførselse til CMC. Bioprocess Research er en del af Recombinant Drug Research, som samarbejder på tværs om at opdage og udvikle terapeutiske kandidater. Vi værdsætter åben kommunikation og opfordrer til vidensdeling mellem medarbejderne. Kreativitet er kernen i vores tilgang til problemløsning, hvilket giver os mulighed for at tackle udfordringer med friske perspektiver. Med et støttende miljø og en fælles forpligtelse til ekspertise stræber vi hele tiden efter at skubbe grænserne for forskning og bidrage til udviklingen af terapeutisk udvikling. Om Novo Nordisk I Novo Nordisk bliver du mødt med tillid, spændende udfordringer og rige muligheder for personlig og faglig udvikling. Du får mulighed for at bringe dine unikke kompetencer i spil i et miljø, hvor sparring og vidensdeling er i højsædet, og hvor din viden og erfaring er værdifuld. Vi er stolte af at bruge vores dedikation og vores evner til at gøre en forskel for millioner af mennesker med diabetes i næsten hele verden. At arbejde her handler ikke bare om at tjene til føden, men om at gøre en forskel.
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