Postdoc in variant-to-function translation in cardiometabolic disease
4 weeks ago
Novo Nordisk Foundation Center for Basic Metabolic Research
University of Copenhagen
We are looking to hire a highly motivated and dynamic researcher with a PhD or equivalent doctorate to join the Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, to work between the Loos Group and the Schéele Group. The candidate should have a strong background in cell and molecular biology. The starting date is March 1, 2023, or after agreement.
The postdoctoral fellowship is offered as part an exciting initiative in close collaboration with the Novo Nordisk Foundation Center for Genomic Mechanisms of Disease (Broad Institute, USA). The candidate will have the opportunity to spend some time in the US, to train at the Broad Institute.
About Us
The Novo Nordisk Foundation Center for Basic Metabolic Research’s vision is to strengthen interdisciplinary research that transforms our basic understanding of the mechanisms that underlie metabolic health and disease, and to accelerate this knowledge toward new prevention and treatment strategies. We were established in 2010 and in 2017, we moved into new laboratories, offices, and meeting rooms in the Maersk Tower . The Center has around 260 employees who work in an international, highly collaborative research environment across a range of biomedical disciplines. You can read more about us here: .
Our Research
The candidate will work between the Loos Group and the Schéele Group at the Novo Nordisk Foundation Center for Basic Metabolic Research. The Loos Group uses genomic, molecular and health data to understand how genetic variants contribute to the risk of cardiometabolic disease. They perform large-scale gene discovery analyses to identify genetic variants associated with cardiometabolic outcomes, followed by bioinformatic analyses to prioritize the most likely candidate gene within each associated locus. The Schéele Group works in close collaboration with clinical departments and develops and exploit human in vitro models including primary cultures and hIPSc programming and differentiation. The group studies the role of brown and white adipose tissue in organ crosstalk and cardiometabolic disease, and address this from a whole-body perspective and down to single cell resolution.
Job Description
The candidate will participate in the translation of genetic discoveries into novel biological insights for cardiometabolic outcomes, in particular obesity and type 2 diabetes. Their main tasks include studying genetic variants by using CrispR technology on human cell models and identifying functional variants. Main target cells include hypothalamic neurons, adipocytes, myocytes, and hepatocytes. Technologies for high-content screening are established and include Maestro Pro multiwell microelectrode array (MEA), ImageXpress Pico and Leica THUNDER Imager Live Cell & 3D Cell Culture & 3D Assay. Functional variants will be further explored in animal models in collaboration with the Rodent metabolic phenotyping platform at CBMR. The postdoc will closely collaborate with the Claussnitzer Group in the Novo Nordisk Foundation Center for Genomic Mechanisms of Disease and have the chance for recurring research visits at the Broad Institute (Cambridge, USA).
Profile
We are looking for a highly motivated and enthusiastic researcher who, in addition to the desired expertise stated above, has the following skills and qualifications:
Required qualifications:
PhD in Functional Genomics, Genetics, Molecular Biology, Molecular Biomedicine Computational Biology, or related sciences Experience in working with transcriptomic or epigenetic data Expertise in mammalian cell culture Expertise in microscopy and imaging techniques, preferably including live cell imaging, 2D/3D imaging, and laser capture techniques. Experience in working with human genetic association data Proven track record showing scientific productivity in peer-reviewed journals. Proficient communication skills and ability to work in multi-disciplinary teams. Experience in supervising other researchers at different levels. Excellent English communication skills, both written and spoken.Terms of Employment
The employment as postdoc is a full-time position for 3 years. Starting date is March 1, 2023, or after agreement.
Salary, pension, and terms of employment will be in accordance with the agreement between the Ministry of Finance and AC (Danish Confederation of Professional Associations). Depending on qualifications, a supplement may be negotiated.
Foreign and Danish applicants may be eligible for tax reductions if they hold a PhD degree and have not lived in Denmark the last 10 years.
The position is covered by the Job Structure for Academic Staff at Universities 2020.
Questions
For further information about the position, please contact Professor Ruth Loos at and Associate Professor Camilla Scheele at . For questions regarding the recruitment procedure, please contact HR at .
The University of Copenhagen International Staff Mobility office offers support and assistance to all international researchers on all issues related to moving to and settling in Denmark. Read more at .
Application Procedure
Your online application must be submitted in English via the ‘Apply now’ link below. Furthermore, your application must include the following documents/attachments – all in PDF format:
Cover letter expressing the motivation and previous research experience of the applicant (max 1 page) Curriculum vitae Copy of the PhD degree certificate and the Master degree certificate. In case the PhD has not yet been completed, a written statement from the supervisor confirming it will be obtained before March 1, 2023, is acceptable. List of publications References (name and contact details of at least two references)Application Deadline: 21 November 2022, 23.59pm CET
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
The Further Process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed, each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.
You can read about the recruitment process at .
The applicant will be assessed according to the Ministerial Order no. 242 of March 13, 2012, on the Appointment of Academic Staff at Universities.
The University of Copenhagen wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of their personal background.
-
København, Denmark Novo Nordisk AS - Nn1 Full timeAre you ready to make a difference in the lives of patients with Diabetes and Obesity? Do you have the commercial expertise to lead and implement strategic initiatives in the Cardiometabolic space? If you are an experienced communicator and thrive in a cross-functional environment, then you might be the perfect fit for our team. Join us as a Commercial...
-
København, Denmark Novo Nordisk AS - Nn1 Full timeAre you ready to make a difference in the lives of patients with Diabetes and Obesity? Do you have the commercial expertise to lead and implement strategic initiatives in the Cardiometabolic space? If you are an experienced communicator and thrive in a cross-functional environment, then you might be the perfect fit for our team. Join us as a Commercial...
-
København, Denmark Novo Nordisk AS - Nn1 Full timeAre you ready to make a difference in the lives of patients with Diabetes and Obesity? Do you have the commercial expertise to lead and implement strategic initiatives in the Cardiometabolic space? If you are an experienced communicator and thrive in a cross-functional environment, then you might be the perfect fit for our team.Join us as a Commercial Senior...
-
København, Denmark Novo Nordisk Full timeAre you ready to make a difference in the lives of patients with Diabetes and Obesity? Do you have the commercial expertise to lead and implement strategic initiatives in the Cardiometabolic space? If you are an experienced communicator and thrive in a cross-functional environment, then you might be the perfect fit for our team. Join us as a Commercial...
-
København, Denmark Novo Nordisk Full timeAre you ready to make a difference in the lives of patients with Diabetes and Obesity? Do you have the commercial expertise to lead and implement strategic initiatives in the Cardiometabolic space? If you are an experienced communicator and thrive in a cross-functional environment, then you might be the perfect fit for our team. Join us as a Commercial...
-
Postdoc within children’s nutrition and health
1 month ago
København, Denmark Københavns Universitet Full timeAre you interested in developing, coordinating and investigating the impact of interventions to promote healthy diets and prevent overweight and lifestyle diseases in children? We are looking for a structured and talented postdoc and project manager for the large partnership project Generation Healthy Kids. You will be employed in the research section...
-
Postdoc within children’s nutrition and health
4 weeks ago
København, Denmark Københavns Universitet Full timeAre you interested in developing, coordinating and investigating the impact of interventions to promote healthy diets and prevent overweight and lifestyle diseases in children? We are looking for a structured and talented postdoc and project manager for the large partnership project Generation Healthy Kids. You will be employed in the research section...
-
København, Denmark Ku - Sund - Panum Kbh N Full timeWe are looking for a Laboratory Assistant to support the work of the Hansen Group at The Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR), to start September 1, 2024, or after agreement. Our research The Novo Nordisk Foundation Center for Basic Metabolic Research’s vision is to pioneer groundbreaking research towards better...
-
Postdoc in Organic Chemistry
4 weeks ago
København, Denmark Ku - Science - Nbi Full timeThe Department of Chemistry, Faculty of Science at University of Copenhagen invites applicants for a one- year Postdoc position in Organic Chemistry. The project is part of the research project “CO2 Capture using new organic materials”, which is financed by Novo Nordisk Foundation CO2 Research Center (CORC), and the research will take part in the group...
-
Postdoc in Organic Chemistry
1 month ago
København, Denmark Ku - Science - Nbi Full timeThe Department of Chemistry, Faculty of Science at University of Copenhagen invites applicants for a one- year Postdoc position in Organic Chemistry. The project is part of the research project “CO2 Capture using new organic materials”, which is financed by Novo Nordisk Foundation CO2 Research Center (CORC), and the research will take part in the group...
-
København, Denmark Københavns Universitet Full timeThe cardiovascular research group is seeking a postdoc in the area of molecular regulation of metabolism and vascular function with a specific focus on the role of mitochondrial peptides. The research involves human experiments, mouse and cellular studies as well as substantial molecular analysis. The duties of the postdoc includes all of these aspects of...
-
København, Denmark Københavns Universitet Full timeThe cardiovascular research group is seeking a postdoc in the area of molecular regulation of metabolism and vascular function with a specific focus on the role of mitochondrial peptides. The research involves human experiments, mouse and cellular studies as well as substantial molecular analysis. The duties of the postdoc includes all of these aspects of...
-
A postdoc in biomechanics and plant microtubules
1 month ago
København, Denmark Københavns Universitet Full timeDepartment of Plant and Environmental Sciences, Section of Plant Glycobiology Faculty of Science at University of Copenhagen is offering a Postdoc position. The postdoc position will be associated with the Plant Cellulose/Cell Biology research group (Prof. Staffan Persson) at the Glycobiology Section. The work aims to understand how certain proteins impact...
-
A postdoc in biomechanics and plant microtubules
4 weeks ago
København, Denmark Københavns Universitet Full timeDepartment of Plant and Environmental Sciences, Section of Plant Glycobiology Faculty of Science at University of Copenhagen is offering a Postdoc position. The postdoc position will be associated with the Plant Cellulose/Cell Biology research group (Prof. Staffan Persson) at the Glycobiology Section. The work aims to understand how certain proteins impact...
-
København K, Denmark KU - SAMF - Psykologi Full timeApplications are invited for a 30 months postdoc in the project 'Improving psychological assessment of face processing across the lifespan' at the Department of Psychology. The project is funded by the Independent Research Fund Denmark.The position starting date is 1 October 2024 or as soon as possible thereafter.Introduction'Improving psychological...
-
Plugin Heat Club
1 month ago
København, Denmark Plug in ApS Full timeLocations: The Plugin Zone (Vasbygade 10A) / Remote / On site at events Company Overview: With a dynamic team of 6 key employees and 25 facilitators, we are creating a new normal for mental and physical health through Saunagus, Icebath and Breathwork sessions. We are looking for a passionate and experienced General Manager to lead our growing team and drive...
-
Plugin Heat Club
4 weeks ago
København, Denmark Plug in ApS Full timeLocations: The Plugin Zone (Vasbygade 10A) / Remote / On site at events Company Overview: With a dynamic team of 6 key employees and 25 facilitators, we are creating a new normal for mental and physical health through Saunagus, Icebath and Breathwork sessions. We are looking for a passionate and experienced General Manager to lead our growing team and drive...
-
Postdoc to LEADership in research programme
1 month ago
København, Denmark Københavns Universitet Full timeThe Postdoc to LEADership in research programme (LEAD) have 12 postdoc positions open at the Biotech Research and Innovation Centre (BRIC), University of Copenhagen Application deadline October 1st, 2022 Are you: Eager to pursue groundbreaking biomedical research? Scientifically curious and driven to pursue a career in research in or beyond...
-
Postdoc to LEADership in research programme
4 weeks ago
København, Denmark Københavns Universitet Full timeThe Postdoc to LEADership in research programme (LEAD) have 12 postdoc positions open at the Biotech Research and Innovation Centre (BRIC), University of Copenhagen Application deadline October 1st, 2022 Are you: Eager to pursue groundbreaking biomedical research? Scientifically curious and driven to pursue a career in research in or beyond...
-
København, Denmark Københavns Universitet Full timeWe are looking for a highly motivated and dynamic researcher at the level of assistant professor for a 2-year position to commence 1 April 2023 or after agreement. The position focus on the research of how astrocytes regulate blood flow during functional hyperaemia. Information on the department can be found at: . Our research group Center for...
