Postdoc in variant-to-function translation in cardiometabolic disease
7 months ago
Novo Nordisk Foundation Center for Basic Metabolic Research
University of Copenhagen
We are looking to hire a highly motivated and dynamic researcher with a PhD or equivalent doctorate to join the Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, to work between the Loos Group and the Schéele Group. The candidate should have a strong background in cell and molecular biology. The starting date is March 1, 2023, or after agreement.
The postdoctoral fellowship is offered as part an exciting initiative in close collaboration with the Novo Nordisk Foundation Center for Genomic Mechanisms of Disease (Broad Institute, USA). The candidate will have the opportunity to spend some time in the US, to train at the Broad Institute.
About Us
The Novo Nordisk Foundation Center for Basic Metabolic Research’s vision is to strengthen interdisciplinary research that transforms our basic understanding of the mechanisms that underlie metabolic health and disease, and to accelerate this knowledge toward new prevention and treatment strategies. We were established in 2010 and in 2017, we moved into new laboratories, offices, and meeting rooms in the Maersk Tower . The Center has around 260 employees who work in an international, highly collaborative research environment across a range of biomedical disciplines. You can read more about us here: .
Our Research
The candidate will work between the Loos Group and the Schéele Group at the Novo Nordisk Foundation Center for Basic Metabolic Research. The Loos Group uses genomic, molecular and health data to understand how genetic variants contribute to the risk of cardiometabolic disease. They perform large-scale gene discovery analyses to identify genetic variants associated with cardiometabolic outcomes, followed by bioinformatic analyses to prioritize the most likely candidate gene within each associated locus. The Schéele Group works in close collaboration with clinical departments and develops and exploit human in vitro models including primary cultures and hIPSc programming and differentiation. The group studies the role of brown and white adipose tissue in organ crosstalk and cardiometabolic disease, and address this from a whole-body perspective and down to single cell resolution.
Job Description
The candidate will participate in the translation of genetic discoveries into novel biological insights for cardiometabolic outcomes, in particular obesity and type 2 diabetes. Their main tasks include studying genetic variants by using CrispR technology on human cell models and identifying functional variants. Main target cells include hypothalamic neurons, adipocytes, myocytes, and hepatocytes. Technologies for high-content screening are established and include Maestro Pro multiwell microelectrode array (MEA), ImageXpress Pico and Leica THUNDER Imager Live Cell & 3D Cell Culture & 3D Assay. Functional variants will be further explored in animal models in collaboration with the Rodent metabolic phenotyping platform at CBMR. The postdoc will closely collaborate with the Claussnitzer Group in the Novo Nordisk Foundation Center for Genomic Mechanisms of Disease and have the chance for recurring research visits at the Broad Institute (Cambridge, USA).
Profile
We are looking for a highly motivated and enthusiastic researcher who, in addition to the desired expertise stated above, has the following skills and qualifications:
Required qualifications:
PhD in Functional Genomics, Genetics, Molecular Biology, Molecular Biomedicine Computational Biology, or related sciences Experience in working with transcriptomic or epigenetic data Expertise in mammalian cell culture Expertise in microscopy and imaging techniques, preferably including live cell imaging, 2D/3D imaging, and laser capture techniques. Experience in working with human genetic association data Proven track record showing scientific productivity in peer-reviewed journals. Proficient communication skills and ability to work in multi-disciplinary teams. Experience in supervising other researchers at different levels. Excellent English communication skills, both written and spoken.Terms of Employment
The employment as postdoc is a full-time position for 3 years. Starting date is March 1, 2023, or after agreement.
Salary, pension, and terms of employment will be in accordance with the agreement between the Ministry of Finance and AC (Danish Confederation of Professional Associations). Depending on qualifications, a supplement may be negotiated.
Foreign and Danish applicants may be eligible for tax reductions if they hold a PhD degree and have not lived in Denmark the last 10 years.
The position is covered by the Job Structure for Academic Staff at Universities 2020.
Questions
For further information about the position, please contact Professor Ruth Loos at and Associate Professor Camilla Scheele at . For questions regarding the recruitment procedure, please contact HR at .
The University of Copenhagen International Staff Mobility office offers support and assistance to all international researchers on all issues related to moving to and settling in Denmark. Read more at .
Application Procedure
Your online application must be submitted in English via the ‘Apply now’ link below. Furthermore, your application must include the following documents/attachments – all in PDF format:
Cover letter expressing the motivation and previous research experience of the applicant (max 1 page) Curriculum vitae Copy of the PhD degree certificate and the Master degree certificate. In case the PhD has not yet been completed, a written statement from the supervisor confirming it will be obtained before March 1, 2023, is acceptable. List of publications References (name and contact details of at least two references)Application Deadline: 21 November 2022, 23.59pm CET
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
The Further Process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed, each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.
You can read about the recruitment process at .
The applicant will be assessed according to the Ministerial Order no. 242 of March 13, 2012, on the Appointment of Academic Staff at Universities.
The University of Copenhagen wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of their personal background.
-
Postdoc in Adipose tissue crosstalk
3 months ago
København, Denmark Københavns Universitet Full timeFaculty of Health and Medical Sciences University of Copenhagen The University of Copenhagen is seeking a highly motivated and talented Postdoc fellow to commence on February 1, 2025, or after agreement in the Schéele Group at the Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR), University of Copenhagen. About Us The Novo Nordisk...
-
Postdoc in adipose mitochondrial biology
3 months ago
København, Denmark Københavns Universitet Full timeNovo Nordisk Foundation Center for Basic Metabolic ResearchUniversity of Copenhagen The University of Copenhagen is seeking an experienced Postdoc fellow to commence on December 1, 2024, or after agreement, for the Gerhart-Hines Group at the Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR), University of Copenhagen. About Us The Novo...
-
Three Group Leaders
3 months ago
København, Denmark Københavns Universitet Full timeThree Group Leaders (Associate Professor or Professor) in Cardiometabolic Health and Disease Three Group Leaders (Associate Professor or Professor) in Cardiometabolic Health and Disease Novo Nordisk Foundation Center for Basic Metabolic ResearchFaculty of Health and Medical SciencesUniversity of Copenhagen The University of Copenhagen seeks to appoint up...
-
København, Denmark Københavns Universitet (KU) Full timeNovo Nordisk Foundation Center for Basic Metabolic Research ,University of Copenhagen We are looking to hire a highly motivated and dynamic Postdoc with a Ph.D. to join the Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Denmark. Candidates should have a strong background in bioinformatics, genomics, multi-omics...
-
København, Denmark Københavns Universitet Full timeThe University uses third-party technologies to register user behaviour on the website (statistics) to keep improving our service. The University also uses third-party technologies to promote degree programmes, courses, conferences and exhibitions on websites and social media to show you the most relevant offers. Postdoctoral Fellowship in Bioinformatics,...
-
København, Denmark Københavns Universitet (KU) Full timeNovo Nordisk Foundation Center for Basic Metabolic Research University of Copenhagen We are looking to hire a highly motivated and dynamic postdoc with a PhD to join the Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Denmark. Candidates should have a strong background in data science, epidemiology, bioinformatics,...
-
Postdoc in Molecular Pharmacology at
3 months ago
København, Denmark Københavns Universitet Full timeThe University uses third-party technologies to register user behaviour on the website (statistics) to keep improving our service. The University also uses third-party technologies to promote degree programmes, courses, conferences and exhibitions on websites and social media to show you the most relevant offers. Department of Drug Design and Pharmacology,...
-
København, Denmark IN-RGY Group Full timePostdoctoral Position in Cancer Immunotherapy: Embark on an exciting research journey in the field of cancer immunotherapy at the National Center for Cancer Immune Therapy (CCIT-DK), Copenhagen University Hospital, Herlev, Denmark. This postdoctoral position offers a unique opportunity to contribute to cutting-edge biomedical research focused on acquired...
-
Postdoc in Molecular Pharmacology at
3 months ago
København, Denmark Københavns Universitet (KU) Full timeDepartment of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen We are looking for a highly motivated and dynamic postdoc who has a strong profile within molecular pharmacology of G protein-coupled receptors (GPCRs) for a 3-year position commencing December 1st, 2024, or as soon as possible thereafter. The...
-
København, Denmark Københavns Universitet Full timePostdoctoral fellowship in data science, epidemiology, bioinformatics, and genomics Novo Nordisk Foundation Center for Basic Metabolic Research University of Copenhagen We are looking to hire a highly motivated and dynamic postdoc with a PhD to join the Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Denmark....
-
København, Denmark Københavns Universitet Full timeThe University uses third-party technologies to register user behaviour on the website (statistics) to keep improving our service. The University also uses third-party technologies to promote degree programmes, courses, conferences and exhibitions on websites and social media to show you the most relevant offers. Postdoc in imaging of synaptic function at...
-
København, Denmark Københavns Universitet (KU) Full timeProject The postdoc will be working on an exciting population genomics project about Greenlandic land mammals, including arctic fox, caribou, arctic hare, wolves, and lemmings. She/he will have the opportunity to analyze several whole genome datasets, which will be ready to be analyzed from day 1. You can read about the project here . It is a collaboration...
-
Postdoc within children’s nutrition and health
7 months ago
København, Denmark Københavns Universitet Full timeAre you interested in developing, coordinating and investigating the impact of interventions to promote healthy diets and prevent overweight and lifestyle diseases in children? We are looking for a structured and talented postdoc and project manager for the large partnership project Generation Healthy Kids. You will be employed in the research section...
-
København, Denmark Københavns Universitet Full timePostdoc in Cancer Epigenetics at Center for Protein Research We are looking for a highly motivated and dynamic postdoc with expertise in chromatin biology to develop new epigenetic approaches for cancer treatment. This is a 3-year position with start 15 November 2024, or after agreement. The successful candidate will work at the Novo Nordisk Foundation...
-
København, Denmark Københavns Universitet (KU) Full timePostdoc in Parasite Immunology at Department of Veterinary and Animal Sciences Faculty of Health and Medical Sciences University of Copenhagen We are looking for a highly motivated and dynamic postdoc for a 2 year position to commence 1 February 2025, or as soon as possible thereafter. The postdoc will be part of the Parasites, Immunology and Gut Health...
-
København, Denmark Københavns Universitet Full timeThe University uses third-party technologies to register user behaviour on the website (statistics) to keep improving our service. The University also uses third-party technologies to promote degree programmes, courses, conferences and exhibitions on websites and social media to show you the most relevant offers. Postdoc in Parasite Immunology at Department...
-
København, Denmark Københavns Universitet (KU) Full timeFaculty of Health and Medical Sciences University of Copenhagen We are looking for a highly motivated and dynamic postdoc for a 3-year position to join the Lund Group. Our research Our team aims to understand how ribosome specialization leads to the instalment of translational programs and how these processes are hijacked in human disease. Due to the...
-
København, Denmark Københavns Universitet Full timeThe University uses third-party technologies to register user behaviour on the website (statistics) to keep improving our service. The University also uses third-party technologies to promote degree programmes, courses, conferences and exhibitions on websites and social media to show you the most relevant offers. Postdoc in Ribosome Specialization in...
-
Laboratory Assistant, Hansen Group
1 month ago
København, Denmark Københavns Universitet Full timeThe Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen We are looking for a Laboratory Assistant to support the work of the Hansen Group at The Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR), to start as soon as possible. Our research The Novo Nordisk Foundation Center for Basic Metabolic Research’s...
-
København, Denmark Københavns Universitet Full timePostdoctoral Fellow for Mass Spectrometry Based Proteomics Investigation of Disease Mechanisms Job Description The Cardiac Proteomics Group at the Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen seeks to appoint a talented postdoctoral fellow to outline protein regulations involved in the pathogenesis of...
