Postdoc in Therapeutic Engineering of iPSC-NK cells
4 days ago
A 2.5-year position for an experienced postdoc is available within the research group 'Biotherapeutic Glycoengineering and Immunology' headed by Professor Steffen Goletz and is funded by the DigitSTEM initiative. Our research group belongs to the Section of Medical Biotechnology at the Department of Biotechnology and Biomedicine.
In our research group, we apply and develop advanced next generation antibody engineering as well as cellular and molecular glycoengineering technologies to elucidate the role of glycosylation's within complex immunological networks and disease and to generate novel therapeutic approaches and drug candidates. Our main therapeutic interest is within immuno-oncology as well as infectious and lung diseases. One focus lies within cellular engineering and glycoengineering of human innate immune cells using gene editing for highly effective cell-based immunotherapeutics and the design and development of their manufacturing processes. Further focus areas are within next generation antibody engineering with bi-/ multi-specific and multimodal antibodies, phage display technologies, exosome engineering and drug delivery, gene therapy, NK- and DC- cell based therapies and their mammalian bioprocess engineering and manufacturing. We also have a strong focus on innovation and entrepreneurship.
The DigitSTEM initiative is a four-year stem cell focused research collaboration between The Technical University of Denmark (DTU), the The Novo Nordisk Foundation Center for Stem Cell Medicine (renew) at University of Copenhagen, and Bioneer A/S that aims at developing new in vitro disease models and therapeutics using human pluripotent stem cells (hPSCs).
The current position focuses on engineering, glycoengineering and differentiation of human induced-pluripotent stem cells (iPSCs) into NK-cells, inducible gene-editing, exosome-based gene editing and bridging activities to our AI-assisted manufacturing approach.
Responsibilities and qualifications
You as the postdoc will work with a team of Senior scientists, postdocs, and PhD students and in close collaboration with academic and industrial collaborators within the DigitSTEM initiative to establish a novel iPSC-derived NK-cell platform for next generation biotherapeutics.
You as the postdoc candidate for this challenging project are highly motivated and must be extensively trained and experienced with a track record in human cell engineering and gene editing, NK cell therapeutics and NK-cell biology, cellular immunology and assay technologies, in vitro 2D- and 3D cancer models, as well as immunooncology in differentiation of NK cells from human iPSCs and within NK-cell biology and assay systems. A prior postdoc in this field is advantageous. Knowledge and skills in stem cell engineering, inducible gene editing technologies, differentiation of NK-cells from iPSC, exosome based gene delivery, antibody and single-domain antibody engineering and discovery, mammalian cell manufacturing, cell-line development, and, glycoengineering, glycoanalytics, and big data analysis will be of great advantage. Moreover, you as the postdoc is expected to contribute to inter connective team tasks as well as in teaching and supervision of PhD, BSc, and MSc students.
You must hold a PhD degree in a relevant life-science discipline (cellular engineering, NK cell or stem cell biology, immunology, immunooncology or alike), have excellent communication skills and be extensively trained in immunology, stem cell biology, cellular engineering, cell culture systems, and computational data analysis.
We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.
Salary and terms of employment
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.
The period of employment is 2.5 years.
Starting date is 1st May 2025 (or according to mutual agreement). The position is a full-time position.
Application procedure
Your complete online application must be submitted no later than 30 March 2025 (23:59 Danish time).
Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply now", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:
- Application (cover letter)
- CV
- Academic Diplomas (MSc/PhD – in English)
- List of publications
Applications received after the deadline will not be considered.
All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply. As DTU works with research in critical technology, which is subject to special rules for security and export control, open-source background checks may be conducted on qualified candidates for the position.
#J-18808-Ljbffr-
Kongens Lyngby, Lyngby-Tårbæk Kommune, Denmark DTU - Technical University of Denmark Full timeJob DescriptionWe are seeking an experienced postdoc to work with us on developing novel therapeutic approaches using human induced-pluripotent stem cells (iPSCs).As a postdoc, you will work with a team of senior scientists, postdocs, and PhD students to establish a novel iPSC-derived NK-cell platform for next-generation...
-
Kongens Lyngby, Lyngby-Tårbæk Kommune, Denmark DTU - Technical University of Denmark Full timeA 3-year Postdoc position for an experienced candidate is available within the research group 'Biotherapeutic Glycoengineering and Immunology' headed by Professor Steffen Goletz and is funded by a NNF Distinguished Innovator grant. Our research group belongs to the Section of Medical Biotechnology at the Department of Biotechnology and Biomedicine. In our...
-
Kongens Lyngby, Lyngby-Tårbæk Kommune, Denmark DTU - Technical University of Denmark Full timeRequired Skills and QualificationsYou must hold a PhD degree in a relevant life-science discipline, such as cellular engineering, NK cell or stem cell biology, immunology, or immunooncology.Excellent communication skills and extensive training in immunology, stem cell biology, cellular engineering, cell culture systems, and computational data analysis.Prior...
-
Kongens Lyngby, Lyngby-Tårbæk Kommune, Denmark DTU - Technical University of Denmark Full timeAre you passionate about advancing fuel cell technologies and contributing to innovative solutions for energy resilience under harsh conditions? Do you thrive in international collaborative settings and wish to play a key role in an EU-funded project with researchers from multiple countries? If so, this postdoc position could be a good opportunity for...
-
Kongens Lyngby, Lyngby-Tårbæk Kommune, Denmark DTU - Technical University of Denmark Full timeAre you passionate about advancing fuel cell technologies and contributing to innovative solutions for energy resilience under harsh conditions? Do you thrive in international collaborative settings and wish to play a key role in an EU-funded project with researchers from multiple countries? If so, this postdoc position could be a good opportunity for you....
-
Kongens Lyngby, Lyngby-Tårbæk Kommune, Denmark Danmarks Tekniske Universitet (DTU) Full timeWe seek a postdoc with expertise in mast cells and/or allergic immune regulation to join our mission to improve the lives of individuals experiencing brain fog in airway allergy and asthma. Are you the next pioneer in the immunology of airway allergy and asthma? We are seeking a curious, talented and pro-active postdoc with a background in immunology,...
-
Kongens Lyngby, Lyngby-Tårbæk Kommune, Denmark Danmarks Tekniske Universitet (DTU) Full timeJob DescriptionWe invite applications for an 18-month postdoctoral position starting as soon as possible. As a postdoc focusing on mast cell regulation in the lung and at the brain borders, you will have ample opportunities for personal development, develop new methods, and use state-of-the-art techniques.Your main tasks will include:To develop, optimize,...
-
Kongens Lyngby, Lyngby-Tårbæk Kommune, Denmark DTU Full timeWe are looking for an ambitious candidate for a Postdoc position in a collaborative research project between the Center for Biosustainability (CfB) at Technical University of Denmark and a consortium consisting of multiple academic partners spread across the EU. In this interdisciplinary research project, our role is to establish engineering pipelines and...
-
Kongens Lyngby, Lyngby-Tårbæk Kommune, Denmark DTU - Technical University of Denmark Full timeThe Department of Energy Conversion and Storage at DTU is seeking a highly motivated postdoctoral researcher to contribute to the development of high-temperature proton exchange membrane (HT-PEM) fuel cell systems. The successful candidate will work on developing and demonstrating a modular, containerized fuel cell system capable of dual-fuel operation with...
-
Kongens Lyngby, Lyngby-Tårbæk Kommune, Denmark DTU - Technical University of Denmark Full timeAbout the PositionWe are seeking a highly motivated and experienced researcher to fill this position. The ideal candidate should have a strong background in multiphysics modeling, simulation, and data analysis. Experience with COMSOL Multiphysics or similar software is highly desirable. Additionally, expertise in electrochemistry, thermodynamics, and fluid...
-
Kongens Lyngby, Lyngby-Tårbæk Kommune, Denmark DTU - Technical University of Denmark Full timeDTU's Department of Energy Conversion and Storage invites applications for a postdoctoral researcher position in the field of high-temperature proton exchange membrane (HT-PEM) fuel cell systems. The successful candidate will work on developing and demonstrating a modular, containerized fuel cell system capable of dual-fuel operation with either hydrogen or...
-
Kongens Lyngby, Lyngby-Tårbæk Kommune, Denmark DTU - Technical University of Denmark Full timeCompany Overview">The Technical University of Denmark (DTU) is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment.Our research group 'Biotherapeutic Glycoengineering and Immunology' is part of the Section...
-
Postdoc position in biocatalysis
1 week ago
Kongens Lyngby, Lyngby-Tårbæk Kommune, Denmark DTU - Technical University of Denmark Full timeWe are searching for a postdoc to join the Enzyme Engineering and Structural Biology research group (EE&SB) of DTU Biosustain. EE&SB focuses on the study, engineering, and application of enzymes to synthesize industrial chemicals, pharmaceuticals, agrochemicals, and nutraceuticals. We use Life Cycle Assessment as a decision-making tool to design sustainable...
-
Kongens Lyngby, Lyngby-Tårbæk Kommune, Denmark Danmarks Tekniske Universitet (DTU) Full timeAre you fascinated with pushing the envelope of what is technologically possible in single-cell proteomics? The Cell Diversity Lab has a 3-year method development PhD position available, embedded within a group focused on development and application of cutting-edge LC-MS technologies. If you are establishing your career as a scientist and are looking for a...
-
Postdoc in Quantum Photonics
1 week ago
Kongens Lyngby, Lyngby-Tårbæk Kommune, Denmark DTU - Technical University of Denmark Full timeAre you passionate about quantum photonics and eager to contribute to groundbreaking research? We offer an exciting opportunity for a postdoc researcher to work on squeezed light sources using the integrated lithium niobate-on-insulator (LNOI) photonics platform at the Technical University of Denmark (DTU)About the ProjectSqueezed light sources are essential...
-
Kongens Lyngby, Lyngby-Tårbæk Kommune, Denmark DTU - Technical University of Denmark Full timeJob DescriptionThe Department of Energy Conversion and Storage at DTU invites applications for a postdoctoral research position focused on modeling and simulation of high-temperature proton exchange membrane (HT-PEM) fuel cells. The successful candidate will contribute to the development of advanced fuel cell systems, exploring novel materials,...
-
PhD Researcher in Single-Cell Proteomics
7 days ago
Kongens Lyngby, Lyngby-Tårbæk Kommune, Denmark Danmarks Tekniske Universitet (DTU) Full timeAbout the PositionThe Department of Biomedical Engineering at Danmarks Tekniske Universitet (DTU) is seeking a highly motivated PhD researcher to join the Cell Diversity Lab. As a part of this team, you will focus on developing novel single-cell proteomics sample preparation techniques using Mass Spectrometry.ResponsibilitiesYou will be responsible for...
-
Postdoc in Biological CO2 Conversion
2 weeks ago
Kongens Lyngby, Lyngby-Tårbæk Kommune, Denmark DTU - Technical University of Denmark Full timeAre you a highly competent, ambitious, and hard-working young scientist wanting to excel in the exciting field of gas fermentation and CO2 utilization in one of the best foundations and collaboration schemes to accomplish this? Then this advertisement is for you.At DTU Chemical Engineering, a postdoc position is available in the frame of a research project...
-
Postdoc in Biological CO2 Conversion
2 days ago
Kongens Lyngby, Lyngby-Tårbæk Kommune, Denmark DTU - Technical University of Denmark Full timeAre you a highly competent, ambitious, and hard-working young scientist wanting to excel in the exciting field of gas fermentation and CO2 utilization in one of the best foundations and collaboration schemes to accomplish this? Then this advertisement is for you.At DTU Chemical Engineering, a postdoc position is available in the frame of a research project...
-
Marine Yeast Cell Factory Specialist
2 days ago
Kongens Lyngby, Lyngby-Tårbæk Kommune, Denmark DTU Full timeAbout the ProjectThis research project aims to establish engineering pipelines for constructing marine yeast cell factories. The project involves a collaborative effort between the Center for Biosustainability at Technical University of Denmark and a consortium of academic partners across the EU.The project's objectives include:Developing and applying...