Principal Scientist, Translational DMPK

1 day ago


København, Denmark H. Lundbeck AS Full time

Do you have experience as DMPK project representative within large molecule drug discovery projects? Then you might just be the new colleague that we are looking for. We have an opening for a Principal Scientist to join Translational DMPK. The department is part of the dynamic Research organization at Lundbeck located in Copenhagen.

Your new role – why is this a great opportunity?

As Principal Scientist you will be involved in guiding the DMPK optimization and characterization of new compounds in our discovery programs. In this role, you will closely interact with DMPK colleagues as well as discovery partners through participation in small multi-disciplinary drug discovery project teams. You will be involved in the entire DMPK discovery value chain from pharmacokinetic screening at early lead stage up to mechanistic and translational investigations at the stage of candidate selection with a focus on our large molecule discovery portfolio. Through your scientific oversight and collaborative spirit, you will play an important role in generating and interpreting value-adding DMPK data to advance our programs.

Your future team

In our department we interact closely with other Research functions such as antibody discovery and engineering, medicinal- and computational chemistry, pharmacology and toxicology to discover and optimize new molecules for CNS diseases. Our team is contributing and influencing the optimization of the DMPK properties of both small and large molecules from early target validation studies through Lead Optimization to selection, profiling, and risk assessment of clinical drug candidates. We are a mix of 14 skilled DMPK and bioanalysis scientists, lab technicians and students working closely together across projects. DMPK research studies and assays are conducted inhouse in modern DMPK and bioanalysis laboratories as well as at specialized CROs around the world. This is a great opportunity to join a research team committed to optimizing the DMPK properties and building the understanding of translation to humans for new molecules targeting CNS diseases.

The position is based at Lundbeck’s headquarters in Valby, Copenhagen.

What you bring to the team

The position requires close scientific and operational coordination within the department as well as close collaboration with discovery project teams and other stakeholders in Research. You enjoy the combination of cross-functional project work, hands-on data analysis, and contributing to devising and implementing DMPK strategies. Further qualifications include:

  • PhD in relevant subject plus at least 6 years of experience in the field of small or large molecule DMPK in the pharmaceutical or biotech industry
  • Experience as DMPK project representative with ability to facilitate DMPK discovery strategies within large molecule-based research projects such as antibodies
  • Expertise with PK analysis of biologics is required as well as understanding of biologics PK/PD reasoning. Knowledge within analytical assays for measuring biologic molecules and biomarkers using mass spectrometry assays in preclinical study samples is desired.

Our promise to you

Lundbeck offers an inspiring workplace, passionate colleagues and a culture characterized as collaborative – a must to successfully bring our treatments through research and development all the way to commercialization and the people who need them. We offer a mix of exciting tasks and numerous development opportunities that are balanced with initiatives focused on your well-being.

Apply now

Can you see yourself in this role? We want to hear from you. Does this sound like your dream job, but you’re not sure if you meet all the requirements? We still want to hear from you

Upload your CV and include a few lines about your motivation for applying. No separate cover letter is needed. We ask you not to include a photo or personal information that does not relate to your professional experience.

If you have questions or want to hear more, please feel free to contact Christoffer Bundgaard, Director, ; +4530835785. Applications must be received by September 16.

We need every brain in the game – and that includes all brains and the different perspectives we bring to the table. At Lundbeck, we embrace the uniqueness of each employee, and we are committed to building a workforce that is as diverse as the people we serve.

#J-18808-Ljbffr

  • København, Denmark Dagens Medicin Full time

    The Faculty of Health and Medical Sciences (SUND) at the University of Copenhagen is seeking 14 highly motivated and dynamic postdoc fellows to commence the BRIDGE – Translational Excellence Programme on 1 September 2025. The BRIDGE – Translational Excellence Programme is financed by the Novo Nordisk Foundation with the ambition to train fellows in...

  • Field Scientist

    5 days ago


    København, Denmark Corteva Agriscience Full time

    As the world’s only major agriscience company completely dedicated to agriculture, we’re building a culture that stays curious, thinks differently, acts boldly and takes a stand on what’s right for our customers, our co-workers, our partners, and our planet. We know we’ve got big challenges to solve – we hope you’ll be part of the solution....


  • København, Denmark momondo Full time

    At KAYAK Concord, KAYAK, part of Booking Holdings (NASDAQ: BKNG), is the world’s leading travel search engine. With billions of queries across our platforms, we help people find their perfect flight, stay, rental car, cruise, or vacation package. We’re also transforming the in-travel experience with our app and new accommodation software. For more...


  • København, Denmark ECCO Sko AS Full time

    Job Openings Apply to become an Operations Research Scientist in our Advanced Analytics & AI team and help build world-class solutions, work with the latest technologies, and enjoy a fun and learning-oriented environment. Join our Data & AI tech hub in Copenhagen We lead the global data science and OR initiatives and capabilities across ECCO Group and drive...


  • København, Denmark Autodesk, Inc. Full time

    Principal Customer Success Manager Principal Customer Success Manager Apply locations EMEA - Sweden - Offsite/Home, EMEA - Denmark - Copenhagen, EMEA - Sweden - Stockholm - Gravlingen, EMEA - Sweden - Gothenburg - Fabriksgatan Job Requisition ID # 24WD83989 Position Overview Real Customer Success comes from the heart. The foundation of our culture is...


  • København, Denmark momondo Full time

    at KAYAK Cambridge KAYAK, part of Booking Holdings (NASDAQ: BKNG), is the world’s leading travel search engine. With billions of queries across our platforms, we help people find their perfect flight, stay, rental car, cruise, or vacation package. We’re also transforming the in-travel experience with our app and new accommodation software. For more...

  • Machine Learning

    4 months ago


    København, Denmark GlobeSearch Management AS Full time

    Company: Grazper Job location: København K Language: English Application deadline: As soon as possible Reporting to: CTO Compensation Package: Attractive compensation package according to qualifications Position: Machine Learning / AI Scientist JOB DESCRIPTION Grazper is seeking a Machine Learning / AI Scientist to join their team of highly talented...


  • København, Denmark momondo Full time

    at KAYAK Concord KAYAK, part of Booking Holdings (NASDAQ: BKNG), is the world’s leading travel search engine. With billions of queries across our platforms, we help people find their perfect flight, stay, rental car, cruise, or vacation package. We’re also transforming the in-travel experience with our app and new accommodation software. For more...


  • København, Denmark Lundbeck AS, H Full time

    In vitro Toxicology Scientist/Specialist - Department of Exploratory Toxicology Requisition ID: 5584 Location: Copenhagen, Danish Capital Region, DK In vitro Toxicology Scientist/Specialist – Department of Exploratory Toxicology As a new colleague in the Department of Exploratory Toxicology, you will join a team of experts who provide toxicological...

  • Data Scientist

    4 months ago


    København, Denmark Trustpilot AS Full time

    We’re a leading online reviews platform, free and open to all. Our mission is to be a universal symbol of trust. We are well on our way — but there’s still an exciting journey ahead of us. Do you want to join us at the heart of trust? From reviews to user behaviors to internal systems, at Trustpilot, we truly have big data. Every month, more than half...


  • København, Denmark Danske Bank Full time

    Ready to Shape the Future of Banking? Join Danske Bank's innovative Digital Transformation and Data Management Team as a Senior Business Analyst! Be at the forefront of technological innovation, harnessing the power of emerging technologies like Generative AI, Automation, and more to revolutionize internal processes within our Risk and Compliance...

  • Head of Fermentation

    4 months ago


    København, Denmark Again Full time

    About Again Again makes carbon negative chemicals for a cleaner future. We are the first carbon negative chemical manufacturer that can scale to meet global demand. The best thing about it: we use carbon dioxide as a feedstock. We have raised over $90m to date from top venture capital investors as well as in grant funding from the European Union’s Horizon...


  • København, Denmark Danske Bank Full time

    Are you a trusted advisor skilled in providing professional support and advice through effective engagement in identifying, assessing, and communicating financial crime risks? Are you a trusted advisor skilled in providing professional support and advice through effective engagement in identifying, assessing, and communicating financial crime risks? The...


  • København, Denmark Københavns Universitet Full time

    The University uses third-party technologies to register user behaviour on the website (statistics) to keep improving our service. The University also uses third-party technologies to promote degree programmes, courses, conferences and exhibitions on websites and social media to show you the most relevant offers. PhD Project in Understanding the Life-Cycle...


  • København, Denmark Genmab Full time

    At Genmab, we’re committed to building extraordinary futures together, by developing antibody products and pioneering therapies that change the lives of patients and the future of cancer treatment and serious diseases. From our people who are caring, candid, and impact-driven to our business, which is innovative and rooted in science, we believe that being...


  • København, Denmark H. Lundbeck AS Full time

    In vitro Toxicology Scientist/Specialist– Department of Exploratory Toxicology As a new colleague in the Department of Exploratory Toxicology, you will join a team of experts who provide toxicological support to all drug research projects at Lundbeck, from the earliest inception of innovative targets to drug candidate selection. Our main task is to...


  • København, Denmark Københavns Universitet (KU) Full time

    Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences University of Copenhagen The University of Copenhagen is seeking a highly motivated and talented Postdoc fellow to commence on February 1, 2025, or after agreement in the Whiteley Group at the Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR)...


  • København, Denmark Novo Holdings AS Full time

    Protein Designer for a New Protein Design Start-up Do you want to help create the next generation of designed biomedicine? Are you eager to work at the cutting edge of computational protein design and high-throughput genomics? Then join us at The BioInnovation Institute (BII) at Nørrebro, where we are currently looking for a Protein Designer. About BII...


  • København, Denmark Pandora AS Full time

    At Pandora, we are transforming the retail experience with cutting-edge technology. Our mission is to provide an exceptional shopping experience to our customers by leveraging data-driven insights and innovative solutions across our business. We are looking for a talented Machine Learning Engineer to join our dynamic team and help us shape the future of...

  • Manager in QC Bioassay

    20 hours ago


    København, Denmark AGC Inc Full time

    Our purpose is to bring hope to life by enabling life-changing therapies for patients around the globe, creating a healthier and happier tomorrow. Our mission is to work side by side with our customers in order to improve patients’ lives by bringing new biopharmaceuticals to market. Do you want to set the direction and drive the development of our new QC...