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Postdoc in Genetic and Molecular Mechanisms of Metabolic Regulation

1 week ago


Copenhagen, Copenhagen, Denmark Københavns Universitet Full time
Postdoc in Genetic and Molecular Mechanisms of Metabolic Regulation

Novo Nordisk Foundation Center for Basic Metabolic Research
University of Copenhagen

The University of Copenhagen is seeking an experienced Postdoc fellow to commence on May 1, 2025, or after agreement, for the Pers Group at the Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR), University of Copenhagen.

About Us
The Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR) is an academic research Center that pioneers groundbreaking research towards better cardiometabolic health. Through collaborative interdisciplinary research from single-cell genomics to whole-body systems, CBMR aims to transform the basic understanding of cardiometabolic health and accelerate its translation into prevention and treatment strategies.

Our Research
The Pers Group investigates the molecular and genetic mechanisms regulating metabolic fuel homeostasis, with a particular focus on the brain's role in metabolic regulation. We integrate human genetics, single-cell multiomics, and advanced model systems to identify and functionally characterize genetic variants associated with metabolic diseases.

Job Description
The Pers Group is seeking a highly motivated postdoctoral fellow to investigate the mechanisms by which human genetic variants associated with obesity influence hypothalamic circuits. This project aims to uncover molecular pathways regulating metabolic homeostasis using a CRISPR-based Perturb-seq system in transgenic animal models. The successful applicant will integrate these approaches with circuit-level readouts, including neuronal activity measurements, and behavioral phenotyping.

Profile
We are looking for a highly motivated and enthusiastic scientist with the following competencies and experience:

  • PhD in molecular biology, neuroscience, biochemistry, or a related field.
  • Strong scientific track record (i.e., publications, training) relative to career stage.
  • Experience with rodent models and in vivo metabolic phenotyping techniques.
  • Strong analytical and problem-solving skills, preferably with experience in computational analysis of sequencing datasets.
  • Excellent English communication skills, both written and oral.

Terms of Employment
The employment as Postdoc is a full-time position for 3 years. The position is covered by the Job Structure for Academic Staff at Universities 2020.

Application Procedure
Your online application must be submitted in English via the 'Apply now' link below. Furthermore, your application must include the following documents/attachments – all in PDF format:

  • Cover letter expressing the motivation and previous research experience of the applicant (max. one page)
  • Copy of the PhD degree certificate and the Master's degree certificate.
  • List of publications
  • References (name and contact details of at least two references)

Application Deadline: 6 March, 23.59pm CET

The University of Copenhagen wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of their personal backgrounds.

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