In Vivo Pharmacology and PK/PD Lead

1 week ago


Copenhagen, Copenhagen, Denmark The Biopôle Full time

The Biopôle is a leading biotech company dedicated to the future of drug discovery by leveraging cutting-edge chemistry and data-driven approaches.

About Our Company

We are committed to transforming the treatment landscape through innovative therapeutics. Our team is at the forefront of this mission.

Job Description:

  1. Developing translational pharmacology plans to support drug candidate progression and collaborating in cross-functional projects as a subject-matter expert.
  2. Building data packages enabling PK/PD understanding and dose-to-man predictions.
  3. Designing, overseeing, and interpreting in vivo pharmacology studies using disease-relevant animal models in collaboration with partners and expert CROs.
  4. Establishing and coordinating activities relating to vivo model development and validation of target engagement and PD biomarker assays.
  5. Identifying and addressing critical biological questions and providing scientific leadership to guide target selection and impact disease indication decisions.
  6. Building and maintaining external networks with expert CROs, collaboration partners, and scientific advisors.

Qualifications:

  1. Ph.D. in biology, biomedicine, or a related field, with at least 8 years of industry experience in Pharma/Biotech, and a strong track record in drug discovery and early development.
  2. Extensive expertise in in vivo pharmacology and PK/PD, including establishment of disease-relevant models and design/interpretation of in vivo studies. Used to managing collaborations with CROs.
  3. Strong background in immunology and translational science, and a deep understanding of immune pathways and mechanisms underlying inflammatory diseases.
  4. Broad experience with end-point analysis and biomarker assays/technologies to support pre-clinical and clinical drug development.
  5. A proactive and flexible team player, with strong collaboration skills, self-leadership, and the ability to manage multiple tasks of varying complexity.
  6. Excellent communication skills, with the ability to present complex scientific data to diverse audiences.


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