In Vivo Pharmacology and PK/PD Lead
1 week ago
The Biopôle is a leading biotech company dedicated to the future of drug discovery by leveraging cutting-edge chemistry and data-driven approaches.
About Our CompanyWe are committed to transforming the treatment landscape through innovative therapeutics. Our team is at the forefront of this mission.
Job Description:
- Developing translational pharmacology plans to support drug candidate progression and collaborating in cross-functional projects as a subject-matter expert.
- Building data packages enabling PK/PD understanding and dose-to-man predictions.
- Designing, overseeing, and interpreting in vivo pharmacology studies using disease-relevant animal models in collaboration with partners and expert CROs.
- Establishing and coordinating activities relating to vivo model development and validation of target engagement and PD biomarker assays.
- Identifying and addressing critical biological questions and providing scientific leadership to guide target selection and impact disease indication decisions.
- Building and maintaining external networks with expert CROs, collaboration partners, and scientific advisors.
Qualifications:
- Ph.D. in biology, biomedicine, or a related field, with at least 8 years of industry experience in Pharma/Biotech, and a strong track record in drug discovery and early development.
- Extensive expertise in in vivo pharmacology and PK/PD, including establishment of disease-relevant models and design/interpretation of in vivo studies. Used to managing collaborations with CROs.
- Strong background in immunology and translational science, and a deep understanding of immune pathways and mechanisms underlying inflammatory diseases.
- Broad experience with end-point analysis and biomarker assays/technologies to support pre-clinical and clinical drug development.
- A proactive and flexible team player, with strong collaboration skills, self-leadership, and the ability to manage multiple tasks of varying complexity.
- Excellent communication skills, with the ability to present complex scientific data to diverse audiences.
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