Pre-Clinical PKPD Modeling Expert
2 days ago
Ascendis Pharma is a biopharmaceutical company applying its TransCon technology to build a leading, fully integrated biopharma company. Guided by patients, science, and passion, we develop new therapies to address unmet medical needs.
We are seeking a skilled pre-clinical and translational PK/PD modeling scientist to join our Pharmacometrics Department. The successful candidate will contribute to advancing drug candidates across Ascendis Pharma's portfolio, focusing on early and translational phases.
The role involves designing and performing drug discovery- and translational PK/PD modeling analyses, maximizing the utility of translational modeling at Ascendis Pharma to impact decision-making in early portfolio activities. You will work with cross-functional teams and external partners, collaborating with colleagues in the Pharmacometrics Department.
Key responsibilities include:
- Conducting PK/PD modeling analyses on early product opportunities
- Performing pre-clinical- and translational PK/PD modeling and simulation analyses to support project decision-making
- Engaging in project teams to design programs and studies to encompass the modeling strategy
- Collaborating with internal and external functional experts on assigned projects
- Maintaining awareness of innovation in the external modeling community
A relevant academic degree (preferably PhD) within pharmaceutical/pharmacokinetic/biological/mathematical science and 3+ years of experience within PK/PD modeling are required. Key skills include hands-on experience and strong programming skills in NONMEM and R language, as well as experience with MIDD and developing models for new target areas.
A strong team player with a can-do attitude is sought after. An entrepreneurial mindset and ability to thrive in an informal environment are also essential. High proactivity, analytical skills, and mathematical background are required. Ability to interpret, summarize, present, and communicate efficiently with scientists from other disciplines is necessary.
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Gentofte, Gentofte Kommune, Denmark Ascendis Pharma AS Full timeAbout the RoleWe are seeking a passionate, hands-on, pre-clinical and translational PK/PD modeling scientist to join our growing Pharmacometrics Department. Your key responsibilities will be:Conduct PK/PD modeling analyses on early product opportunitiesPerform pre-clinical and translational PK/PD modeling and simulation analyses to support project...
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