PhD Position in Urine Peptide-Based Classifiers for CKD Understanding
3 weeks ago
This is a 3-year PhD position as part of the European Doctoral Network (DN) program entitled "Personalized Medicine in Chronic Kidney Disease (PICKED)". The program involves 10 research centers from France, Austria, Spain, Greece, Germany, Denmark, and Estonia.
The PhD position is hosted at Steno Diabetes Center Copenhagen, Denmark. The PhD student will work on investigating urinary peptide patterns and the effect of different contemporary treatments to increase understanding of specific beneficial pathways that treatments affect and explore kidney-specific mechanisms through which these compounds act.
The main objectives of the PhD will be:
- To collect existing data from cohorts with renal follow-up to expand previous analyses and perform detailed exploration of available data.
- To measure urinary proteomics patterns in stored samples from intervention trials with SGLT2 inhibitors and GLP-receptor agonists aiming to understand at least part of the mechanism behind the renal benefit seen with these drugs.
- To explore performance of recently developed classifiers in the collected cohorts with urinary proteomic data available.
The PhD student will mostly work on data and statistical analysis, interpretation of the clinical aspects of the results, and conveying the implications to people with CKD.
The PhD student will be enrolled in a PhD programme at the Copenhagen University and supervised by Peter Rossing and Tine Willum Hansen from Steno Diabetes Center Copenhagen and Paul Perco from University of Heidelberg.
The PhD student will also participate in the weekly web-seminars of the collaborative network of the laboratory and attend yearly meetings organised by the PICKED consortium.
The PhD student must not have a doctoral degree at the date of their recruitment and must comply with the mobility rule: not have resided or carried out their main activity (work, studies, etc.) in Denmark for more than 12 months in the 36 months immediately before the recruitment date.
The PhD student will benefit from all Marie Skłodowska-Curie Action scheme advantages.
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