Team Manager Purification

15 hours ago

Ballerup, Denmark Symphogen AS Full time

Team Manager Purification - Apply your managerial and scientific skills to make a significant impact in an innovative environment dedicated to developing antibodies.

Symphogen is in an exciting phase as the Antibody Center of Excellence in Servier, with a continued focus on the development of antibody-based therapeutic products for the treatment of cancer and inflammatory/autoimmune diseases.

As Team Manager Purification , you will lead the highly skilled Purification team, which is responsible for the downstream process development of monoclonal antibodies, as well as novel antibody formats, including bispecifics and ADCs.

With direct report to the Director CMC, Drug Substance Development, you will enter a role with a high degree of cross-functional collaboration with the two other CMC departments, Drug Product Development and Analytical Chemistry, along with colleagues from research and external CMOs.

Examples of key responsibilities (not limited to):

  • Timely material supply supporting lead candidate selection in the discovery phase
  • In-house downstream process development for early and late-stage clinical programs
  • Technology transfer to CMOs and oversight of outsourced activities
  • Process characterization and validation for late-stage programs
  • Contribute to the downstream development strategy including next generations of antibody formats such as bispecific antibodies and ADCs
  • Project/development of specific tasks as purification scientist/SME

To thrive in this position, you have extensive hands-on experience in the pharmaceutical/biotech industry within the downstream process development of antibody products. Ideally, you have managerial experience, e.g., from a line function or a project team. Experience with novel antibody formats such as bispecific and ADCs, as well as late-stage process characterization and validation, is advantageous. You should also have knowledge about GMP requirements, preparation of regulatory documentation, and collaboration/oversight with outsourced activities to CMOs.

You have a relevant master’s degree in pharmaceuticals, biologics, or similar, and you are fluent in English, in speech and writing.

You are a person who gets involved in your surroundings and has a pragmatic and proactive style of work. You are good at setting directions and encourage initiative and team collaboration through a coaching management style.

Symphogen offers a challenging and versatile job in an innovative, flexible, focused, and committed biotech environment with a meaningful mission: to advance superior monoclonal antibody therapeutics to improve the lives of patients. Moreover, Symphogen offers strong cross-functional teamwork, room for individual performance and development, and passionate, inspiring, and fun colleagues.

Travelling: Limited. Approx. ten days per year.

Domicile: Ballerup, Denmark.

For more details about the job or the company, please contact CEO Jørn Duhn, Unique Human Capital, at M: +45 21 75 19 25 or Senior Research Consultant Caroline Krüger, Unique Human Capital, at E: All applications must be in English and are treated confidentially.

Apply:

Company
Symphogen is a subsidiary of Servier and antibody center of excellence primarily focused on oncology and immune oncology. We have a highly efficient antibody discovery and research platform supported by comprehensive early development capabilities.

Our antibody platform delivers antibodies with unique functionalities providing best or first in class potential as combination or mono therapy. Our approach and capabilities are well suited for combination therapies at the core of future cancer treatment.

Symphogen is located in Ballerup in the greater Copenhagen area. The company currently employs approximately 150 people.

We aim to attract employees who can challenge the status quo in the pursuit of excellence.

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