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Postdoctoral Researcher in Bacterial Antibiotic Resistance
2 months ago
A fully funded 2-year postdoctoral position is available in the Department of Veterinary and Animal Sciences at the University of Copenhagen. The project, "Breaking Antimicrobial Resistance by Targeting Potentiators", is funded by the Independent Research Fund Denmark (FTP) and involves leading researchers from the University of Copenhagen, the University of Southern Denmark, Statens Serum Institute, the University of Greifswald, and Harvard Medical School.
The project aims to combat antimicrobial resistance by delineating the molecular mechanisms of bacterial resistance. The postdoctoral fellow will investigate how the Spx-controlled bacterial stress response potentiates both virulence and antimicrobial resistance in methicillin-resistant Staphylococcus aureus (MRSA). The laboratory work will include state-of-the-art molecular methods in microbiology and immunology, as well as advanced microscopy.
Project DescriptionOne of the biggest challenges in modern healthcare is the increasing number of bacterial infections not responding to antibiotic treatment. This clinical challenge is compounded by the lack of mechanistic understanding of bacterial resistance. The objective of the project is to combat antimicrobial resistance by delineating the molecular mechanisms whereby intrinsic bacterial factors, so-called "potentiators", allow bacteria to develop high-level resistance to antibiotics.
The GroupThe project will be supervised by Associate Professor Dorte Frees, who has extensive experience in the molecular biology of antibiotic resistance and the pathogenesis of bacterial pathogens. The FreesLab has a strong focus on doing excellent science in an open, collaborative, and sustainable work environment, and in supporting each member's individual career goals.
Required Qualifications- A PhD degree in molecular microbiology, preferably within a topic of relevance to the project subject.
- Solid experience in relevant methodologies such as bacterial molecular biology, functional genomics, protein biochemistry, microscopy, and/or antibiotic resistance mechanisms.
- Hands-on experience with bioinformatic genomic analyses.
- A documented publication record, preferably with at least one first-author paper in an international peer-reviewed biological journal.
- An open-minded and enthusiastic personality.
- Ability to work independently and efficiently as part of a team.
- Excellent English communication skills, both oral and written.
- An interest in teaching.
The application must be in English and include the following documents in PDF format:
- Motivated letter of application (max. one page).
- CV incl. education, experience, language skills, and other skills relevant for the position.
- A certified copy of PhD certificate and Master of Science certificate. If the PhD is not completed, a certified/signed copy of a recent transcript of records or a written statement from the supervisor will do.
- List of publications.
The place of employment is at the Department of Veterinary and Animal Sciences, University of Copenhagen. We offer creative and stimulating working conditions in a dynamic and international research environment. Our research facilities include modern laboratories and state-of-the-art equipment.
The employment as postdoc is a full-time and fixed-term position for 2 years. Starting date is January 1st, 2025, or as soon as possible hereafter. Salary, pension, and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations).
