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Data Scientist in Genomics and Metabolic Diseases
1 month ago
We are seeking a highly motivated and talented Data Scientist to join our team at the Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen. As a Data Scientist, you will work on a project that aims to integrate high-throughput mass spectrometry (MS)-based plasma proteomics data with electronic health registry data, along with genetic information from 4,180 Greenlandic individuals.
Job DescriptionThe successful candidate will have a background in data science or bioinformatics and be familiar with integrative research approaches within the broad area of basic cardiometabolic research. You will examine baseline and longitudinal associations between the MS-based plasma proteome and cardiometabolic disease outcomes using registry-based data.
Furthermore, you will perform a Genome-Wide Association Study (GWAS) of the MS-based plasma proteome to identify protein quantitative trait loci (pQTLs), and examine the overlap between pQTLs and cardiometabolic disease-associated risk variants using colocalization methods.
Your Tasks- Examine baseline and longitudinal associations between the MS-based plasma proteome and cardiometabolic disease outcomes using registry-based data.
- Perform a GWAS of the MS-based plasma proteome to identify protein quantitative trait loci (pQTLs).
- Examine the overlap between pQTLs and cardiometabolic disease-associated risk variants using colocalization methods.
- PhD in bioinformatics, computational biology, statistical genomics or similar.
- Proficiency in a high-level programming language such as R or Python.
- Experience in applying statistical methods to proteomic and/or genomic data.
- Experience from working with large genomic datasets.
- Proven track record showing scientific productivity in peer-reviewed journals.
The Novo Nordisk Foundation Center for Basic Metabolic Research is an academic research center that pioneers groundbreaking research towards better cardiometabolic health. Through collaborative interdisciplinary research from single-cell genomics to whole-body systems, we aim to transform the basic understanding of cardiometabolic health and accelerate its translation into prevention and treatment strategies.
Salary and BenefitsWe offer a competitive salary of DKK 550,000 - 720,000 per year, depending on your experience and qualifications. Additionally, you will receive a generous pension scheme and access to our comprehensive benefits package.
