Genetic Regulation Specialist in Cardiometabolic Disease

4 days ago


Copenhagen, Copenhagen, Denmark Københavns Universitet Full time

The University of Copenhagen is committed to advancing cardiometabolic health through cutting-edge research. We are seeking a highly motivated Postdoc fellow to join our team at the Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR).

Job Description

Company Overview

The CBMR is an academic research center that pioneers groundbreaking research towards better cardiometabolic health. Our team combines research in genetics, physiology, and pharmacology to better understand the complex interplay of factors driving cardiometabolic disease.

About the Job

We are looking for a talented researcher with a background in data science or bioinformatics to work on a project integrating high-throughput mass spectrometry-based plasma proteomics data with electronic health registry data. The goal is to drive the discovery of novel clinical biomarkers and therapeutic targets for cardiometabolic diseases, including obesity, type 2 diabetes, and cardiovascular diseases.

Your Tasks

  • Examine baseline and longitudinal associations between the MS-based plasma proteome and cardiometabolic disease outcomes using registry-based data.
  • Perform a GWAS of the MS-based plasma proteome to identify protein quantitative trait loci (pQTLs).
  • Examine the overlap between pQTLs and cardiometabolic disease-associated risk variants using colocalization methods.
  • Coordinate project-related tasks.
  • Contribute to scientific papers.

Requirements

  • PhD in bioinformatics, computational biology, statistical genomics, or similar.
  • Proficiency in a high-level programming language such as R or Python.
  • Experience in applying statistical methods to proteomic and/or genomic data.
  • Experience from working with large genomic datasets.
  • Proven track record showing scientific productivity in peer-reviewed journals.
  • Excellent English communication skills, both written and oral.

What We Offer

A competitive salary range: DKK 446,850 - 549,099 per year, depending on experience and qualifications. A full-time position for 3 years. Starting date: February 1, 2025, or after agreement.

How to Apply

Please submit your online application via the 'Apply now' link below. Your application must include:

  • Cover letter expressing motivation and previous research experience.
  • Copy of PhD degree certificate and master's degree certificate.
  • List of publications.
  • References (name and contact details of at least two references).


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