Neuroscience Research Position

4 days ago


Copenhagen, Copenhagen, Denmark Københavns Universitet Full time
About the Position

We are seeking a highly motivated and dynamic researcher to join our team at the Department of Neuroscience. The position involves conducting single cell mRNA sequencing studies, performing in vivo imaging of the dorsal root ganglion in anesthetized mice using multiphoton imaging, and collaborating with researchers within the department and external collaborators.

The research group focuses on fundamental aspects of basic pharmacology, molecular pharmacology, and neuropharmacology, with certain translational aspects. The work is divided into three Work Packages each containing a number of specific projects.

  • Work Package 1 is focused on the pharmacology of PSD95/Disc-large/ZO-1 homology (PDZ) mediated proteins-protein interaction and how these domains might represent new attractive pharmacological targets as alternatives to surface receptors.
  • Work Package 2 seeks to understand the role of protein-membrane interactions in the context of synaptic transmission and generation of Large Dense Core vesicles.
  • Work Package 3 is aimed at obtaining fundamental new understanding of dopamine signaling processes in the brain and its relation to PKA signaling.

Methodologically, we specialize in molecular biology, protein purification, receptor binding, advanced light microscopy, including live microscopy and fluorescence energy transfer microscopy (FRET), as well as trafficking assays of integral membrane proteins using ELISA and confocal microscopy. We also have experience with transgenic mouse models and various behavioral readouts.

The successful candidate will be expected to conceptualize and design innovative research projects aligned with the group's focus areas, collaborate with international researchers, and disseminate results at seminars, conferences, and for the general public.



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