Postdoctoral Researcher in Cancer Epigenetics

1 month ago

Odense, Odense Kommune, Denmark Hs Mittweida Full time
Job Description

We are seeking a highly motivated and experienced Postdoctoral Researcher to join our team in Cancer Epigenetics. The successful candidate will lead research on gene regulatory mechanisms underlying cancer metastasis and drug resistance, and will support Professor Tiwari in the smooth running of the laboratory.

Key Responsibilities
  • Lead research on gene regulatory mechanisms in cancer metastasis and chemoresistance
  • Employ state-of-the-art methods in epigenetics and gene regulation, including histone modification, transcription factor binding, and chromatin accessibility assays
  • Design research projects and support in establishing complex molecular biology protocols
  • Perform in vitro and in vivo experiments as necessary
  • Support research and development activities within the group
  • Support the group leader in everyday routines, including training new group members
  • Maintain accurate and detailed records of all research activities within the group
  • Collaborate with internal and external partners
  • Engage in teaching as required
  • Conduct collaborative research and interact with a broad range of colleagues and researchers
Requirements
  • PhD in molecular biology, epigenetics, chromatin biology, genomics, cancer biology, biochemistry, developmental biology, or related areas
  • At least one first-author publication, accepted or submitted
  • Strong analytical, organizational, and record-keeping skills
  • Proficient computer skills, including MS Office and research software programs
  • Interest in working in a multidisciplinary and multicultural team
  • Willing to collaborate with internal and external collaborators as well as support group members
Desirable Qualifications
  • Basic understanding of cancer biology and gene regulation
  • Conceptual grip on cancer genetics, epigenetics, and gene regulation
  • Experience in cell culture as well as basic and advanced molecular biology techniques
  • Familiarity with organoids/spheroids and mouse models
  • Prior experience with perturbation-based functional analysis (e.g. shRNA, CRISPR-Cas9)
  • Familiarity with drug sensitivity assays and screening
  • Expertise in tissue sectioning, immunostaining, and advanced imaging (e.g. confocal microscopy)
  • Basic understanding of bioinformatics would be an advantage
About the Department

The Department of Molecular Medicine (IMM) aims to generate new knowledge on the function of the human body and disease mechanisms, thereby contributing to improved human health. IMM hosts an interdisciplinary group of experts in cancer biology and is in close proximity to experts in genomics, proteomics, and chromatin biology.

What We Offer
  • The possibility to engage in high-impact, multidisciplinary research
  • A stimulating, diverse, and international research environment
  • An initial contract for six months, with the possibility of extension for three years
  • Advanced training opportunities
  • Highly motivated research team and international collaborations
  • Access to state-of-the-art equipment and facilities
  • A supportive scientific and social network, including mentoring and career development
  • A competitive salary and social benefits (e.g. health coverage, parental leave, social security, etc.)
  • Support with practical, social, and legal aspects (e.g. housing, visa, tax, etc.) through our international staff office (ISO) and the department

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