Cardiovascular Disease Biologist

2 weeks ago


Copenhagen, Copenhagen, Denmark Københavns Universitet (KU) Full time

About the Hansen Group

The Hansen Group is part of the Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR) at Københavns Universitet (KU). Our research focuses on understanding the complex interplay between genetics, physiology, and pharmacology in the context of cardiometabolic disease.

We are currently seeking a highly motivated Postdoctoral Fellow to join our team and contribute to a project that aims to drive the discovery of novel clinical biomarkers and therapeutic targets for cardiometabolic diseases. The successful candidate will have the opportunity to work on an exciting project that integrates high-throughput mass spectrometry-based plasma proteomics data with electronic health registry data, along with genetic information from 4,180 Greenlandic individuals.

About the Project

The project involves examining baseline and longitudinal associations between the MS-based plasma proteome and cardiometabolic disease outcomes using registry-based data, performing a GWAS of the MS-based plasma proteome to identify protein quantitative trait loci (pQTLs), examining the overlap between pQTLs and cardiometabolic disease-associated risk variants using colocalization methods, coordinating project-related tasks, and contributing to scientific papers.

Requirements

  • PhD in bioinformatics, computational biology, statistical genomics or similar
  • Proficiency in a high-level programming language such as R or Python
  • Experience in applying statistical methods to proteomic and/or genomic data
  • Experience working with large genomic datasets
  • Proven track record showing scientific productivity in peer-reviewed journals
  • Strong coordination skills
  • Excellent English communication skills, both written and oral

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