Research Associate in Proteomics and Metabolism
1 week ago
The Role
We are seeking a highly motivated Postdoctoral Fellow to join the Hansen Group at the Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR). The successful candidate will have the opportunity to work on an exciting project that integrates high-throughput mass spectrometry-based plasma proteomics data with electronic health registry data, along with genetic information from 4,180 Greenlandic individuals.
The project aims to drive the discovery of novel clinical biomarkers and therapeutic targets for cardiometabolic diseases, including obesity, type 2 diabetes (T2D), and cardiovascular diseases (CVDs). The successful candidate will be responsible for examining baseline and longitudinal associations between the MS-based plasma proteome and cardiometabolic disease outcomes using registry-based data, performing a GWAS of the MS-based plasma proteome to identify protein quantitative trait loci (pQTLs), examining the overlap between pQTLs and cardiometabolic disease-associated risk variants using colocalization methods, coordinating project-related tasks, and contributing to scientific papers.
Key Responsibilities
- Examine baseline and longitudinal associations between the MS-based plasma proteome and cardiometabolic disease outcomes using registry-based data
- Perform a GWAS of the MS-based plasma proteome to identify protein quantitative trait loci (pQTLs)
- Examine the overlap between pQTLs and cardiometabolic disease-associated risk variants using colocalization methods
- Coordinate project-related tasks
- Contribute to scientific papers
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