PhD scholarship in Enzyme Engineering of Carbohydrate-Active Enzymes

1 month ago

Kongens Lyngby, Denmark DTU Full time

PhD scholarship in engineering of carbohydrate active enzymes active to harness them as tools for synthesis of biotechnologically and biomedically important oligosaccharides in the Protein Glycoscience and Biotechnology group, DTU Bioengineering. This project, which is funded by Independent Research Fund Denmark | Technology and Production Research Project 1, is in collaboration with excellent national and international partners and aims at establishing a new strategy to engineer enzymes for synthesis of a variety of important oligosaccharides.

If your ambition is to 1) Work with cutting-edge strategies for enzyme engineering with an international top-notch research team, 2) Innovate sustainable solutions to harness the most abundant and renewable resources on the globe, namely carbohydrates, and 3) To communicate novel scientific findings and solutions, then this is the right project for you to set up your scientific career.

Responsibilities and qualifications
The overarching aim of your project is to develop and apply new approaches for rational engineering of carbohydrate active enzymes. This will be based on both molecular knowledge from X-ray structures and in silico computational techniques and protein design tools, which will be key to the project. A short research stay at the lab of an external collaboration partner is expected in the project.

Your academic and personal profile:

  • An academic record with a solid background in protein chemistry and biophysics is critical, preferably within carbohydrate-active enzymes and/or carbohydrate chemistry.
  • Skills in bioinformatics and programming are major assets.
  • Hard-working, motivated, ambitious and aiming for excellence. In addition, you need to thrive both working independently and together with research teams within an international environment, where you will work with at least two different laboratories within the project.
  • Open to contributing to teaching and undergraduate supervision related to your project.

You must have a two-year master's degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master's degree.

Approval and Enrolment
The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see DTU's rules for the PhD education .

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

Salary and appointment terms
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 3 years.

The start of the PhD project is in March 2025 or another close date per mutual agreement.

Further information
Further information may be obtained from Professor Maher Abou Hachem, email: .

Application procedure
Your complete online application must be submitted no later than 15 December 2024 (23:59 Danish time) .

Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply now", fill out the online application form, and attach all your materials in English in one PDF file . The file must include:

  • A letter motivating the application (cover letter)
  • Curriculum vitae
  • Grade transcripts and BSc/MSc diploma (in English) including official description of grading scale. The grades need to be translated to the Danish grade system using an Excel sheet available online.
  • Two-three references and potential recommendation letters if available.

You may apply prior to obtaining your master's degree but cannot begin before having received it.

Applications received after the deadline will not be considered.

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply. As the position involves research in critical technology, which is subject to special rules for security and export control, among other things, open-source background checks will be conducted on qualified candidates for the position.

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