Bioinformatics Researcher for Exploration of the Dark Genome

1 month ago


Hellerup, Gentofte Kommune, Denmark Rigshospitalet - Blegdamsvej Full time
Job Description

We are seeking a highly skilled bioinformatics researcher to join our team at Rigshospitalet - Blegdamsvej. The successful candidate will contribute to a project aimed at defining cell stress states associated with HERV-K expression and sensitivity to HERV-K variations that triggers immunogenic cell death.

Key Responsibilities:
  • Conduct bioinformatics analysis of RNA sequencing data to identify differentially expressed genes and pathways associated with HERV-K expression.
  • Develop and implement bioinformatics tools and pipelines to analyze large datasets and identify potential therapeutic targets.
  • Collaborate with the Fase 1 Unit at Department of Oncology and the Danish Biotech startup Hervolution to advance our understanding of HERV-K's role in cell stress and immunogenic cell death.
  • Contribute to the development of innovative immunotherapeutic strategies for the treatment of cancers.
Requirements:
  • Master degree or equivalent in Bioinformatics or a related field.
  • Strong background in bioinformatics, with prior experience in RNA sequencing data and differential expression analysis.
  • Proficiency in bioinformatics tools and programming languages such as R, Python, and relevant RNA-seq analysis pipelines.
  • Experience with handling large datasets and data harmonization.
  • Expertise in genomic analysis and variant calling is a plus.
Application Process:

Interested candidates should submit the following:

  • A cover letter detailing their research experience and how it aligns with needed qualifications for the project.
  • A curriculum vitae (CV) and full publication list (if applicable).
  • Contact information for at least three professional references.

We look forward to receiving your application and exploring the possibility of working together to advance our understanding of HERV-K's role in cell stress and immunogenic cell death.



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