Bioinformatics Researcher for Exploration of the Dark Genome
1 month ago
We are seeking a highly skilled bioinformatics researcher to join our team at Rigshospitalet - Blegdamsvej. The successful candidate will contribute to a project aimed at defining cell stress states associated with HERV-K expression and sensitivity to HERV-K variations that triggers immunogenic cell death.
Key Responsibilities:- Conduct bioinformatics analysis of RNA sequencing data to identify differentially expressed genes and pathways associated with HERV-K expression.
- Develop and implement bioinformatics tools and pipelines to analyze large datasets and identify potential therapeutic targets.
- Collaborate with the Fase 1 Unit at Department of Oncology and the Danish Biotech startup Hervolution to advance our understanding of HERV-K's role in cell stress and immunogenic cell death.
- Contribute to the development of innovative immunotherapeutic strategies for the treatment of cancers.
- Master degree or equivalent in Bioinformatics or a related field.
- Strong background in bioinformatics, with prior experience in RNA sequencing data and differential expression analysis.
- Proficiency in bioinformatics tools and programming languages such as R, Python, and relevant RNA-seq analysis pipelines.
- Experience with handling large datasets and data harmonization.
- Expertise in genomic analysis and variant calling is a plus.
Interested candidates should submit the following:
- A cover letter detailing their research experience and how it aligns with needed qualifications for the project.
- A curriculum vitae (CV) and full publication list (if applicable).
- Contact information for at least three professional references.
We look forward to receiving your application and exploring the possibility of working together to advance our understanding of HERV-K's role in cell stress and immunogenic cell death.
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Hellerup, Gentofte Kommune, Denmark Rigshospitalet - Blegdamsvej Full timeHuman endogenous retroviruses (HERVs) are a significant component of the human genome, with HERV-K being a particularly interesting subset. This project aims to explore the role of HERV-K in cell stress and immunogenic cell death, with the ultimate goal of developing innovative immunotherapeutic strategies.We are seeking a highly skilled bioinformatics...
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