Postdoctoral Researcher in Genetic Regulation of the Plasma Proteome
2 weeks ago
We are seeking a highly motivated and talented Postdoctoral Researcher to join our team at the Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR) at the University of Copenhagen. The successful candidate will work on a project that aims to integrate high-throughput mass spectrometry (MS)-based plasma proteomics data with electronic health registry data, along with genetic information from 4,180 Greenlandic individuals to drive the discovery of novel clinical biomarkers and therapeutic targets for cardiometabolic diseases.
Research FocusThe Postdoctoral Researcher will be part of the Hansen Group, which focuses on bridging the gap between basic genetic and microbiome discoveries and their impact on physiology and clinical translation. The group uses a combination of genomic discoveries, epidemiology, physiology, and clinical application to study the role of selected genetic variants in human metabolism.
Responsibilities- Examine baseline and longitudinal associations between the MS-based plasma proteome and cardiometabolic disease outcomes using registry-based data.
- Perform a GWAS of the MS-based plasma proteome to identify protein quantitative trait loci (pQTLs).
- Examine the overlap between pQTLs and cardiometabolic disease-associated risk variants using colocalization methods.
- Coordinate project-related tasks.
- Contribute to scientific papers.
- PhD in bioinformatics, computational biology, statistical genomics, or a related field.
- Proficiency in a high-level programming language such as R or Python.
- Experience in applying statistical methods to proteomic and/or genomic data.
- Experience from working with large genomic datasets.
- Proven track record of scientific productivity in peer-reviewed journals.
- Strong coordination skills.
- Excellent English communication skills, both written and oral.
The Postdoctoral Researcher position is open to applicants who hold a PhD degree awarded from a university outside of Denmark. The program is also open to applicants with a Danish PhD degree who can document at least 12 months of full-time research experience from outside Denmark during or after the PhD studies.
Terms of EmploymentThe employment as Postdoctoral Researcher is a full-time position for 3 years. Starting date is February 1, 2025, or after agreement.
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