Breakthrough in Single-Cell Proteomics: PhD Scholarship Opportunity
1 day ago
Danmarks Tekniske Universitet (DTU), a leading technical university globally recognized for its excellence in research, education, innovation, and scientific advice.
Salary and BenefitsThe appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 3 years. Estimated salary range: DKK 60,000 - 80,000 per month (approximately USD 8,800 - 12,000). A competitive pension scheme, health insurance, and access to a comprehensive benefits package are also offered.
Job DescriptionThis PhD scholarship opportunity is part of DTU's major long-term strategy to combine experimental and computational approaches to establish single-cell proteomics as a routine tool for deciphering cell heterogeneity in complex biological systems. The project primarily focuses on developing novel sample preparation methods, including enrichment of post-translational modifications, for conducting high-throughput single-cell proteomics experiments.
Responsibilities and Qualifications- Develop and implement novel mass spectrometry data acquisition strategies to explore their application in low-input proteomics down to single cells.
- Design and optimize low-volume liquid handling approaches to develop next-generation single-cell proteomics sample preparation workflows that can be combined with PTM-enrichment.
- Explore novel chromatography approaches to enhance sensitivity for single-cell proteomics.
The ideal candidate should hold a two-year master's degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master's degree. Relevant subject areas include biochemistry, biomedicine, medicinal chemistry, molecular biology, immunology, or related subjects. The candidate should have a strong interest in fundamental scientific discoveries and elevating their translational potential. Prior experience with single-cell proteomics method development, LC-MS, mammalian cell culture techniques, automated low-volume liquid handling, cell sorting equipment, FACS, and computational/bioinformatics analysis of proteomics datasets is highly desirable.
BenefitsAs a researcher at DTU, you will have the opportunity to work in a dynamic and international environment. You will be part of a vibrant community of researchers and students working together to push the boundaries of knowledge and innovation. Additionally, you will have access to a comprehensive benefits package, including a competitive salary, pension scheme, health insurance, and opportunities for professional development.
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