Postdoctoral Researcher in Cardiometabolic Genomics and Proteomics

4 weeks ago


Copenhagen, Copenhagen, Denmark Københavns Universitet (KU) Full time

About the University of Copenhagen

The University of Copenhagen is a leading international research university, ranking among the top universities globally. The institution aims to foster a collaborative and inclusive environment that promotes excellence in teaching, research, and community engagement.

Job Overview

We are seeking a highly motivated and talented Postdoctoral Research Fellow to join our team at the Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR) within the Faculty of Health and Medical Sciences. This position is part of the CBMR International PhD & Postdoc Program.

About the Project

The Postdoctoral Research Fellow will work on a cutting-edge project integrating high-throughput mass spectrometry (MS)-based plasma proteomics data with electronic health registry data, along with genetic information from 4,180 Greenlandic individuals. The goal is to drive the discovery of novel clinical biomarkers and therapeutic targets for cardiometabolic diseases, including obesity, type 2 diabetes (T2D), and cardiovascular diseases (CVDs).

Responsibilities

  • Examine baseline and longitudinal associations between the MS-based plasma proteome and cardiometabolic disease outcomes using registry-based data.
  • Perform a Genome-Wide Association Study (GWAS) of the MS-based plasma proteome to identify protein quantitative trait loci (pQTLs).
  • Examine the overlap between pQTLs and cardiometabolic disease-associated risk variants using colocalization methods.
  • Coordinate project-related tasks.
  • Contribute to scientific papers.

Requirements

  • A PhD in bioinformatics, computational biology, statistical genomics or similar.
  • Proficiency in a high-level programming language such as R or Python.
  • Experience in applying statistical methods to proteomic and/or genomic data.
  • Experience working with large genomic datasets.
  • A proven track record showing scientific productivity in peer-reviewed journals.
  • Strong coordination skills.
  • Excellent English communication skills, both written and oral.

Eligibility

The Postdoctoral Research Fellowships within the CBMR International PhD & Postdoc Program are open for applicants holding a PhD degree awarded from a university outside of Denmark or with a Danish PhD degree who can document at least 12 months of full-time research experience from outside Denmark during or after the PhD studies.

Terms of Employment

The employment as Postdoctoral Research Fellow is a full-time position for 3 years. Starting date is February 1, 2025, or after agreement.

Estimated Salary

The estimated salary for this position is approximately $60,000 - $80,000 per annum, depending on qualifications and experience.



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